Evidence map›Paper›PMID 33916276›Full record

ArticleJournal of clinical medicine2021

Does the Age Affect the Outcomes of Cardiac Resynchronization Therapy in Elderly Patients?

Teresa Strisciuglio, Giuseppe Stabile, Domenico Pecora, Giuseppe Arena, Salvatore Ivan Caico, Massimiliano Marini, Patrizia Pepi, Antonio D'Onofrio, Antonio De Simone, Giuseppe Ricciardi and 11 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 11 institutions in 1 country.

Teresa StrisciuglioDepartment of Advanced Biomedical Sciences, Federico II University of Naples, 80138 Naples, Italy.
Giuseppe StabileMontevergine Clinic, 83013 Mercogliano, Italy.
Domenico PecoraFondazione Poliambulanza, 25124 Brescia, Italy.
Giuseppe ArenaDepartment of Cardiology, Apuane Hospital, 54100 Massa, Italy.ORCID 0000-0002-0266-6493
Salvatore Ivan CaicoDepartment of Cardiology, ASST Valle Olona, Gallarate Hospital, 21013 Gallarate, Italy.
Massimiliano MariniDepartment of Cardiology, Santa Chiara Hospital, 38122 Trento, Italy.
Patrizia PepiOspedale Carlo Poma, 46100 Mantua, Italy.
Antonio D'OnofrioOspedale Monaldi, 80131 Naples, Italy.
Antonio De SimoneClinica San Michele, 81024 Maddaloni, Italy.
Giuseppe RicciardiHeart and Vessels Department, University of Florence, 50121 Firenze, Italy.
Sandra BadolatiOspedale Sant'Andrea, 19121 La Spezia, Italy.
Alfredo SpottiIstituti Ospitalieri, 26100 Cremona, Italy.
Gavino CasuDepartment of Cardiology, Ospedale San Francesco, 08100 Nuoro, Italy.
Francesco SolimeneMontevergine Clinic, 83013 Mercogliano, Italy.
Carmelo La GrecaFondazione Poliambulanza, 25124 Brescia, Italy.ORCID 0000-0003-2692-7333
Giuseppe AmmiratiDepartment of Advanced Biomedical Sciences, Federico II University of Naples, 80138 Naples, Italy.ORCID 0000-0002-7440-1793
Valerio PergolaDepartment of Advanced Biomedical Sciences, Federico II University of Naples, 80138 Naples, Italy.
Lucio AddeoDepartment of Advanced Biomedical Sciences, Federico II University of Naples, 80138 Naples, Italy.
Maurizio MalacridaBoston Scientific Italia, 20134 Milan, Italy.
Emanuele BertagliaDepartment of Cardiac, Thoracic, and Vascular Sciences, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-3878-2904
Antonio RapacciuoloDepartment of Advanced Biomedical Sciences, Federico II University of Naples, 80138 Naples, Italy.ORCID 0000-0002-4739-7004
University of Naples Federico II · ITFondazione Poliambulanza Istituto Ospedaliero · ITAzienda Ospedaliera Carlo Poma · ITAzienda Ospedaliera Sant'Andrea · ITAzienda Ospedaliera Sant’Antonio Abate di Gallarate · ITCasa di Cura San Michele · ITIstituti Ospitalieri di Cremona · ITOspedale Monaldi · ITOspedale Santa Chiara · ITUniversity of Florence · ITUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMore and more heart failure (HF) patients aged ≥ 75 years undergo cardiac resynchronization therapy (CRT) device implantation, however the data regarding the outcomes and their predictors are scant. We investigated the mid- to long-term outcomes and their predictors in CRT patients aged ≥ 75 years.

methodsPatients in the Cardiac Resynchronization Therapy Modular (CRT MORE) Registry were divided into three age-groups: <65 (group A), 65-74 (group B) and ≥75 years (group C). Mortality, hospitalization, and composite event rate were evaluated at 1 year and during long-term follow-up.

resultsPatients (

conclusionPositive clinical response and hospitalization rates do not differ between CRT recipients ≥ 75 years and those aged 65-74. However, age > 80 years, COPD and CKD are predictors of worse outcomes.

Indexed as

cardiac resynchronization therapyclinical responseelderlyheart failureoutcomes

Identifiers

PMID33916276
PMCPMC8036418
OpenAlexW3146764577

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.