Evidence map›Paper›PMID 33916266›Full record

ArticleJournal of clinical medicine2021

Are Differences in Presentation of Early Lyme Borreliosis in Europe and North America a Consequence of a More Frequent Spirochetemia in American Patients?

Vera Maraspin, Petra Bogovič, Katarina Ogrinc, Tereza Rojko, Eva Ružić-Sabljić, Andrej Kastrin, Klemen Strle, Gary P Wormser, Franc Strle

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Lyme borreliosis.Nature reviews. Disease primers · 2026
    Review
  2. Review
  3. Article
  4. Colocalization of Radicular Pain and Erythema Migrans in Patients With Bannwarth Syndrome Suggests a Direct Spread of Borrelia Into the Central Nervous System.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022
    Article
  5. Seasonality of Acute Lyme Disease in Children.Tropical medicine and infectious disease · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Vera MaraspinDepartment of Infectious Diseases, University Medical Center Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.
Petra BogovičDepartment of Infectious Diseases, University Medical Center Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.
Katarina OgrincDepartment of Infectious Diseases, University Medical Center Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.ORCID 0000-0002-8134-749X
Tereza RojkoDepartment of Infectious Diseases, University Medical Center Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.
Eva Ružić-SabljićInstitute for Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Zaloška cesta 4, 1000 Ljubljana, Slovenia.ORCID 0000-0001-7906-555X
Andrej KastrinInstitute for Biostatistics and Medical Informatics, Faculty of Medicine, University of Ljubljana, Vrazov trg 2, 1000 Ljubljana, Slovenia.ORCID 0000-0002-3495-0165
Klemen StrleLaboratory of Microbial Pathogenesis and Immunology, Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, 120 New Scotland Ave, Albany, NY 12208, USA.
Gary P WormserDivision of Infectious Diseases, New York Medical College, Valhalla, NY 10595, USA.
Franc StrleDepartment of Infectious Diseases, University Medical Center Ljubljana, Japljeva 2, 1525 Ljubljana, Slovenia.ORCID 0000-0003-4163-0503
Ljubljana University Medical Centre · SIUniversity of Ljubljana · SINew York Medical College · USNew York State Department of Health · US

Funding

Javna Agencija za Raziskovalno Dejavnost RS P3-0296
6 · The paper itself

Abstract

To assess whether differences in presentation between US and European patients with early Lyme borreliosis are due to the lower rate of spirochetemia in Europe, we compared multiple variables for patients with erythema migrans (EM), restricting the analysis to subjects with a positive blood culture at the time of presentation: 93 US patients infected with

Indexed as

bloodBorrelia afzeliiBorrelia burgdorferiBorrelia gariniiEuropeisolationLyme borreliosisUSA

Identifiers

PMID33916266
PMCPMC8037040
OpenAlexW3142463326

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.