ArticleMicroorganisms2021
Serotype Distribution of Remaining Pneumococcal Meningitis in the Mature PCV10/13 Period: Findings from the PSERENADE Project.
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Article in Microorganisms, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
0numbers the graph read from it
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28citing papers in PubMed, 1 pooled it
6.8field-weighted citation impact, top 2% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Serotype distribution of invasive and non-invasive pneumococcal disease in adults ≥65 years of age following the introduction of 10- and 13-valent pneumococcal conjugate vaccines in infant national immunization programs: a systematic literature review.Frontiers in public health · 2025Pooled it
- Immunogenicity and safety of a multi-human dose formulation of Biological E's 14-valent pneumococcal polysaccharide conjugate vaccine (PNEUBEVAX 14Frontiers in immunology · 2025Trial
- Pneumococcal meningitis among hospitalised children after introduction of pneumococcal conjugate vaccine in India: a sentinel hospital surveillance (2019-2022).The Lancet regional health. Southeast Asia · 2026Article
- Invasive Pneumococcal Disease Epidemiology and Conjugate Vaccines in Canada, 2000-2019.JAMA network open · 2026Article
- A novel real-time PCR assay for the simultaneous detection of the four main causes of bacterial meningitis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2026Article
- Synthesis and Immunogenicity of Pseudo-Oligosaccharides Structurally Related to Repeating Units of Capsular Phosphoglycans of Human Pathogens.Molecules (Basel, Switzerland) · 2025Review
- Evolving Landscape of Paediatric Pneumococcal Meningitis in Argentina (2013-2023).Microorganisms · 2025Article
- Inference of Pairwise Interactions from Strain Frequency Data Across Settings and Context-Dependent Mutual Invasibilities.Bulletin of mathematical biology · 2025Article
- Serotype distribution of remaining invasive pneumococcal disease after extensive use of ten-valent and 13-valent pneumococcal conjugate vaccines (the PSERENADE project): a global surveillance analysis.The Lancet. Infectious diseases · 2025Article
- Global impact of 10- and 13-valent pneumococcal conjugate vaccines on pneumococcal meningitis in all ages: The PSERENADE project.The Journal of infection · 2025Article
- Serotype 3 Streptococcus pneumoniae Escapes the Immune Responses Induced by PCV13 in Mice With High Susceptibility to Infection.Immunity, inflammation and disease · 2024Article
- Observational
- The single D380 amino acid substitution increases pneumolysin cytotoxicity toward neuronal cells.iScience · 2024Article
- Serotype distribution, clinical characteristics, and antimicrobial resistance of pediatric invasive pneumococcal disease in Colombia during PCV10 mass vaccination (2017-2022).Frontiers in medicine · 2024Article
- Co-occurrence of bacteria and viruses and serotype distribution ofFrontiers in public health · 2024Article
- Serotype epidemiology and antibiotic resistance of pneumococcal isolates colonizing infants in Botswana (2016-2019).PloS one · 2024Article
- Comparison of next generation technologies and bioinformatics pipelines for capsular typing ofJournal of clinical microbiology · 2023Article
- Article
- Systematic Literature Review of the Epidemiological Characteristics of Pneumococcal Disease Caused by the Additional Serotypes Covered by the 20-Valent Pneumococcal Conjugate Vaccine.Microorganisms · 2023Review
- Optimal age targeting for pneumococcal vaccination in older adults; a modelling study.Nature communications · 2023Article
Corrections and comments
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Authors and funding
50 authors at 20 institutions in 30 countries.
Maria Garcia QuesadaJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0002-0206-7597
Yangyupei YangJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Julia C BennettJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0003-2559-2922
Kyla HayfordJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0002-9872-2313
Scott L ZegerJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Daniel R FeikinIndependent Consultant, 1296 Coppet, Switzerland.
Meagan E PetersonJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0001-6562-2730
Adam L CohenWorld Health Organization, 1202 Geneva, Switzerland.
Samanta C G AlmeidaCenter of Bacteriology, National Laboratory for Meningitis and Pneumococcal Infections, Institute Adolfo Lutz (IAL), São Paulo 01246-902, Brazil.
Krow AmpofoDepartment of Pediatrics, Division of Pediatric Infectious Diseases, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA.
Michelle AngNational Centre for Infectious Diseases, National Public Health Laboratory, Singapore 308442, Singapore.
Naor Bar-ZeevJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Michael G BruceNational Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Arctic Investigations Program, Division of Preparedness and Emerging Infections, Anchorage, AK 99508, USA.ORCID 0000-0001-8275-3484
Romina CamilliDepartment of Infectious Diseases, Italian National Institute of Health (Istituto Superiore di Sanità, ISS), 00161 Rome, Italy.
Grettel Chanto ChacónInstituto Costarricense de Investigación y Enseñanza en Nutrición y Salud, Tres Ríos, 30301 Cartago, Costa Rica.
Pilar CiruelaCIBER Epidemiología y Salud Pública, (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0003-0842-7220
Cheryl CohenCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, 2192 Johannesburg, South Africa.ORCID 0000-0003-0376-2302
Mary CorcoranIrish Meningitis and Sepsis Reference Laboratory, Children's Health Ireland at Temple Street, Temple Street, D01 YC76 Dublin 1, Ireland.ORCID 0000-0002-6669-9083
Ron DaganDistinguished Professor of Pediatrics and Infectious Diseases, The Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Philippe De WalsDepartment of Social and Preventive Medicine, Laval University, Québec, QC G1V 0A6, Canada.
Stefanie DesmetDepartment of Microbiology, Immunology and Transplantation, KU Leuven, 3000 Leuven, Belgium.
Idrissa DiawaraFaculty of Sciences and Health Techniques, Mohammed VI University of Health Sciences (UM6SS) of Casablanca, 20250 Casablanca, Morocco.ORCID 0000-0003-4122-2294
Ryan GierkeNational Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
Marcela GuevaraCIBER Epidemiología y Salud Pública, (CIBERESP), 28029 Madrid, Spain.ORCID 0000-0001-9242-6364
Laura L HammittJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.
Markus HiltySwiss National Reference Centre for Invasive Pneumococci, Institute for Infectious Diseases, University of Bern, 3012 Bern, Switzerland.ORCID 0000-0002-2418-6474
Pak-Leung HoDepartment of Microbiology and Carol Yu Centre for Infection, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China.ORCID 0000-0002-8811-1308
Sanjay JayasingheNational Centre for Immunisation Research and Surveillance and Discipline of Child and Adolescent Health, Faculty of Medicine and Health, Children's Hospital Westmead Clinical School, University of Sydney, Westmead, NSW 2145, Australia.
Jackie KleynhansCentre for Respiratory Diseases and Meningitis, National Institute for Communicable Diseases of the National Health Laboratory Service, 2192 Johannesburg, South Africa.ORCID 0000-0001-7081-6273
Karl G KristinssonDepartment of Clinical Microbiology, Landspitali-The National University Hospital, Hringbraut, 101 Reykjavik, Iceland.
Shamez N LadhaniImmunisation and Countermeasures Division, Public Health England, London NW9 5EQ, UK.
Allison McGeerToronto Invasive Bacterial Diseases Network, and Department of Laboratory, Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada.
Jason M MwendaWorld Health Organization Regional Office for Africa, P.O. Box 06, Brazzaville, Congo.
J Pekka NuortiDepartment of Health Security, Finnish Institute for Health and Welfare, 00271 Helsinki, Finland.
Kazunori OishiToyama Institute of Health, Imizu, Toyama 939-0363, Japan.ORCID 0000-0001-5919-7520
Leah J RicketsonDepartment of Pediatrics, University of Calgary, Calgary, AB T3B 6A8, Canada.ORCID 0000-0003-1369-8391
Juan Carlos SanzLaboratorio Regional de Salud Pública, Dirección General de Salud Pública, Comunidad de Madrid, 28053 Madrid, Spain.ORCID 0000-0002-1453-8536
Larisa SavrasovaCentre for Disease Prevention and Control of Latvia, 1005 Riga, Latvia.
Lena Petrova SetchanovaDepartment of Medical Microbiology, Faculty of Medicine, Medical University of Sofia, 1431 Sofia, Bulgaria.
Andrew SmithBacterial Respiratory Infection Service, Scottish Microbiology Reference Laboratory, NHS GG&C, Glasgow G4 0SF, UK.ORCID 0000-0003-0580-4078
Palle Valentiner-BranthInfectious Disease Epidemiology and Prevention, Statens Serum Institut, DK-2300 Copenhagen S, Denmark.
Maria Teresa ValenzuelaDepartment of Public Health and Epidemiology, Faculty of Medicine, Universidad de Los Andes, 12455 Santiago, Chile.
Mark van der LindenNational Reference Center for Streptococci, Department of Medical Microbiology, University Hospital RWTH Aachen, 52074 Aachen, Germany.
Nina M van SorgeMedical Microbiology and Infection Prevention, Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam University Medical Centers, Location AMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.ORCID 0000-0002-2695-5863
Emmanuelle VaronNational Reference Centre for Pneumococci, Centre Hospitalier Intercommunal de Créteil, 94000 Créteil, France.ORCID 0000-0002-3043-2838
Brita A WinjeDepartment of Infection Control and Vaccine, Norwegian Institute of Public Health, 0456 Oslo, Norway.
Inci YildirimDepartment of Pediatrics, Yale New Haven Children's Hospital, New Haven, CT 06504, USA.ORCID 0000-0002-8631-0020
Jonathan ZintgraffServicio de Bacteriología Clínica, Departamento de Bacteriología, INEI-ANLIS "Dr. Carlos G. Malbrán", C1282 AFF Buenos Aires, Argentina.
Maria Deloria KnollJohns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA.ORCID 0000-0001-9041-2671
The Pserenade Team
Johns Hopkins University · USCenters for Disease Control and Prevention · USNational Health Laboratory Service · ZAAdministración Nacional de Laboratorios e Institutos de Salud · ARAmsterdam University Medical Centers · NLBen-Gurion University of the Negev · ILCentro de Investigación Biomédica en Red de Epidemiología y Salud Pública · ESComunidad de Madrid · ESHôpital Intercommunal de Créteil · FRInstituto Adolfo Lutz · BRInstituto Costarricense de Investigación y Enseñanza en Nutrición y Salud · CRInstituto de Salud Pública de Navarra · ESIstituto Superiore di Sanità · ITKU Leuven · BEMedical University of Sofia · BGNational Centre for Infectious Diseases · SGNational University Hospital of Iceland · ISNorwegian Institute of Public Health · NOPublic Health England · GBQueen Mary Hospital · CN
Funding
Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9MBill and Melinda Gates Foundation INV-010429 / OPP1189065NCATS NIH HHS UL1 TR001863World Health Organization 001
Abstract
Pneumococcal conjugate vaccine (PCV) introduction has reduced pneumococcal meningitis incidence. The Pneumococcal Serotype Replacement and Distribution Estimation (PSERENADE) project described the serotype distribution of remaining pneumococcal meningitis in countries using PCV10/13 for least 5-7 years with primary series uptake above 70%. The distribution was estimated using a multinomial Dirichlet regression model, stratified by PCV product and age. In PCV10-using sites (
Indexed as
globalmeta-analysisPCV impactpneumococcal meningitisserotype distribution
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