Evidence map›Paper›PMID 33916192›Full record

Trial reportNutrients2021

The Effectiveness of Probiotic

Bożena Cukrowska, Aldona Ceregra, Elżbieta Maciorkowska, Barbara Surowska, Maria Agnieszka Zegadło-Mylik, Ewa Konopka, Ilona Trojanowska, Magdalena Zakrzewska, Joanna Beata Bierła, Mateusz Zakrzewski and 2 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06035835 (Probiotics and Breastmilk Are Associated With a Decreased Risk of Atopic Dermatitis in Very Low Birth Weight Premature Infants), which is not on this map. Cited by 51 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 6 pooled it
13.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06035835 completednot on this map

Probiotics and Breastmilk Are Associated With a Decreased Risk of Atopic Dermatitis in Very Low Birth Weight Premature Infants

TypeobservationalSponsorJosé Uberos FernándezRan2009 to 2022Enrolled437ConditionsAtopic DermatitisArmsLacticaseibacillus rhamnosus, Lactobacillus acidophilus + Bifidobacterium bifidum
3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 6 syntheses or guidelines pooled it, 94 citations in OpenAlex.

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  7. Effects ofFoods (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Bożena CukrowskaDepartment of Pathomorphology, the Children's Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw, Poland.
Aldona CeregraOutpatient Allergology and Dermatology Clinic, Patriotów St. 100, 04-844 Warsaw, Poland.
Elżbieta MaciorkowskaDepartment of Developmental Age Medicine and Paediatric Nursing, Faculty of Health Sciences, Medical University of Bialystok, Szpitalna St. 37, 15-295 Białystok, Poland.
Barbara SurowskaOutpatient Allergology Clinic, the Children's Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw, Poland.
Maria Agnieszka Zegadło-MylikOutpatient Dermatology Clinic, Chodakowska St. 8, 96-503 Sochaczew, Poland.
Ewa KonopkaDepartment of Pathomorphology, the Children's Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw, Poland.
Ilona TrojanowskaDepartment of Pathomorphology, the Children's Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw, Poland.
Magdalena ZakrzewskaDepartment of Developmental Age Medicine and Paediatric Nursing, Faculty of Health Sciences, Medical University of Bialystok, Szpitalna St. 37, 15-295 Białystok, Poland.
Joanna Beata BierłaDepartment of Pathomorphology, the Children's Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw, Poland.ORCID 0000-0002-5772-5091
Mateusz ZakrzewskiDepartment of Developmental Age Medicine and Paediatric Nursing, Faculty of Health Sciences, Medical University of Bialystok, Szpitalna St. 37, 15-295 Białystok, Poland.
Ewelina KanarekDepartment of Pathomorphology, the Children's Memorial Health Institute, Aleja Dzieci Polskich 20, 04-730 Warsaw, Poland.
Ilona MotylDepartment of Environmental Biotechnology, Lodz University of Technology, Wólczańska 171/173, 90-924 Łódź, Poland.
Children's Memorial Health Institute · PLMedical University of Białystok · PLLodz University of Technology · PL

Funding

Narodowe Centrum Badań i Rozwoju NR12-0101-10/2011the Children's Memorial Health Institute S168/2020
6 · The paper itself

Abstract

Probiotics seem to have promising effects in the prevention and treatment of allergic conditions including atopic dermatitis (AD) and food allergy. The purpose of this multicenter randomized placebo-controlled trial was to evaluate the effectiveness of a probiotic preparation comprising

Indexed as

Lacticaseibacillus caseiLacticaseibacillus rhamnosusAllergensAnimalsCattleDermatitis, AtopicDouble-Blind MethodHumansInfantMilk HypersensitivityProbioticsAllergensatopic dermatitiscow’s milk protein allergyfood allergyLactobacillus caseiLactobacillus rhamnosusprobiotics

Identifiers

PMID33916192
PMCPMC8066586
OpenAlexW3143487286

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.