Evidence map›Paper›PMID 33916187›Full record

ArticleCells2021

Effect of Hydrocortisone on Angiotensinogen (

Min-Hua Tseng, Shih-Ming Huang, Martin Konrad, Jing-Long Huang, Steven W Shaw, Ya-Chung Tian, Ho-Yen Chueh, Wen-Lang Fan, Tai-Wei Wu, Jhao-Jhuang Ding and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 3 countries.

Min-Hua TsengDivision of Nephrology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan 330, Taiwan.
Shih-Ming HuangDepartment of Biochemistry, National Defense Medical Center, Taipei 114, Taiwan.ORCID 0000-0001-9305-921X
Martin KonradDepartment of General Pediatrics, University Children's Hospital Münster, 481 Münster, Germany.
Jing-Long HuangDivision of Pediatric Allergy, Asthma, and Rheumatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan 330, Taiwan.
Steven W ShawDepartment of Obstetrics and Gynecology, Taipei Chang Gung Memorial Hospital and Chang Gung University, Taipei 114, Taiwan.ORCID 0000-0002-3931-7297
Ya-Chung TianDivision of Nephrology, Department of Medicine, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan 330, Taiwan.
Ho-Yen ChuehDepartment of Obstetrics and Gynecology, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan 330, Taiwan.
Wen-Lang FanGenomic Medicine Core Laboratory, Chang Gung Memorial Hospital, Taoyuan 333, Taiwan.
Tai-Wei WuFetal and Neonatal Institute, Division of Neonatology Children's Hospital Los Angeles, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 900, USA.ORCID 0000-0001-5155-6189
Jhao-Jhuang DingDepartment of Pediatrics, Tri-Service General Hospital, Taipei 114, Taiwan.
Ming-Chou ChiangDivision of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital and Chang Gung University, Taoyuan 330, Taiwan.
Shih-Hua LinDivision of Nephrology, Department of Medicine, Tri-Service General Hospital, Taipei 114, Taiwan.
Chang Gung University · TWTri-Service General Hospital · TWChang Gung Memorial Hospital · TWNational Defense Medical Center · TWUniversity Hospital Münster · DEUniversity of Southern California · US

Funding

Ministry of Science and Technology (MOST 109-2314-B-182A-134-MY3)
6 · The paper itself

Abstract

We has identified a founder homozygous E3_E4 del: 2870 bp deletion + 9 bp insertion in

Indexed as

Genes, RecessiveAngiotensinogenBase SequenceCell LineDNA, ComplementaryHumansHydrocortisoneKidneyKidney Tubules, ProximalLiverModels, BiologicalMutant ProteinsMutationProtein BindingProtein StabilityReceptors, GlucocorticoidAngiotensinogenDNA, ComplementaryHydrocortisoneMutant ProteinsReceptors, GlucocorticoidReninangiotensinogenfounder effectrenal tubular dysgenesisrescue therapy

Identifiers

PMID33916187
PMCPMC8065467
OpenAlexW3140974514

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.