Evidence map›Paper›PMID 33916132›Full record

ArticleVaccines2021

HPV Type-Specific Prevalence a Decade after the Implementation of the Vaccination Program: Results from a Pilot Study.

Clara Fappani, Silvia Bianchi, Donatella Panatto, Fabio Petrelli, Daniela Colzani, Stefania Scuri, Maria Gori, Antonella Amendola, Iolanda Grappasonni, Elisabetta Tanzi and 1 more

Open access · goldAbstract read
In one paragraph

Article in Vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Human Papillomavirus: An Old New History.Pathogens (Basel, Switzerland) · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Prevalence of Human Papillomavirus Genotypes in Tehran, Iran.Journal of research in health sciences · 2022
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Clara FappaniDepartment of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.
Silvia BianchiDepartment of Health Sciences, University of Milan, 20142 Milan, Italy.ORCID 0000-0002-1365-9408
Donatella PanattoDepartment of Health Sciences, University of Genoa, 16100 Genoa, Italy.ORCID 0000-0002-2677-0551
Fabio PetrelliSchool of Medicinal and Health Products Sciences, University of Camerino, 62032 Camerino, Italy.
Daniela ColzaniDepartment of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.
Stefania ScuriSchool of Medicinal and Health Products Sciences, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0003-4518-1653
Maria GoriDepartment of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.ORCID 0000-0001-6478-2791
Antonella AmendolaDepartment of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.
Iolanda GrappasonniSchool of Medicinal and Health Products Sciences, University of Camerino, 62032 Camerino, Italy.ORCID 0000-0003-1131-4286
Elisabetta TanziDepartment of Biomedical Sciences for Health, University of Milan, 20133 Milan, Italy.ORCID 0000-0002-4119-701X
Daniela AmiciziaDepartment of Health Sciences, University of Genoa, 16100 Genoa, Italy.ORCID 0000-0002-9707-5214
University of Milan · ITUniversità di Camerino · ITUniversity of Genoa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human papillomavirus infection is a cause of the development of invasive cervical cancer. Three types of vaccine are currently available to prevent precancerous/cancerous lesions due to persistent infection, which is supported mainly by 7 different high-risk genotypes. The aim of this pilot study was to acquire preliminary data on type-specific prevalence 10 years after the implementation of the HPV vaccination program in Italy, in order to subsequently plan appropriate observational studies in the Italian population. First-voided urine samples were collected from 393 consenting subjects, both females and males, aged 18-40 years, and HPV DNA was detected by PCR amplification of a 450 bp L1 fragment. All amplified products were genotyped by means of the Restriction Fragment Length Polymorphism (RFLP) method. The female population was divided into three cohorts ("vaccine-eligible", "pre-screening" and "screening" cohorts) according to the preventive intervention scheduled by age; males were included in the same three cohorts according to their year of birth. The overall prevalence of HPV infection was 19%, being higher in females than in males (22.1% vs. 13.6%,

Indexed as

HPV genotype distributionHPV infectionItalyurine samplesvaccine-preventable diseases

Identifiers

PMID33916132
PMCPMC8066234
OpenAlexW3142937508

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.