Evidence map›Paper›PMID 33916097›Full record

ArticleMolecules (Basel, Switzerland)2021

The Potential of Parsley Polyphenols and Their Antioxidant Capacity to Help in the Treatment of Depression and Anxiety: An In Vivo Subacute Study.

Imane Es-Safi, Hamza Mechchate, Amal Amaghnouje, Omkulthom Mohamed Al Kamaly, Fatima Zahra Jawhari, Hamada Imtara, Andriy Grafov, Dalila Bousta

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Review
  3. Plants (Basel, Switzerland) · 2023
    Article
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  7. Root Vegetables-Composition, Health Effects, and Contaminants.International journal of environmental research and public health · 2022
    Review
  8. Article
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  10. Review
  11. Efficiency ofEvidence-based complementary and alternative medicine : eCAM · 2022
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Protective Effect ofTheScientificWorldJournal · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 4 countries.

Imane Es-SafiLaboratory of Biotechnology, Environment, Agri-Food and Health (LBEAS), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University (USMBA), Fez 30050, Morocco.ORCID 0000-0002-9239-3045
Hamza MechchateLaboratory of Biotechnology, Environment, Agri-Food and Health (LBEAS), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University (USMBA), Fez 30050, Morocco.ORCID 0000-0003-4571-9089
Amal AmaghnoujeLaboratory of Biotechnology, Environment, Agri-Food and Health (LBEAS), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University (USMBA), Fez 30050, Morocco.ORCID 0000-0002-4759-3312
Omkulthom Mohamed Al KamalyDepartment of Pharmaceutical Sciences, College of Pharmacy, Princess Nourah Bint Abdulrahman University, Riyadh 11564, Saudi Arabia.
Fatima Zahra JawhariLaboratory of Biotechnology, Environment, Agri-Food and Health (LBEAS), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University (USMBA), Fez 30050, Morocco.ORCID 0000-0003-1622-4490
Hamada ImtaraFaculty of Arts and Sciences, Arab American University Palestine, Jenin 240, Palestine.ORCID 0000-0002-8410-3212
Andriy GrafovDepartment of Chemistry, University of Helsinki, 00100 Helsinki, Finland.
Dalila BoustaLaboratory of Biotechnology, Environment, Agri-Food and Health (LBEAS), Faculty of Sciences Dhar El Mahraz, Sidi Mohamed Ben Abdellah University (USMBA), Fez 30050, Morocco.
Sidi Mohamed Ben Abdellah University · MAArab American University · PSPrincess Nourah bint Abdulrahman University · SAUniversity of Helsinki · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Depression and anxiety are major mental health problems in all parts of the world. These illnesses are associated with a number of risk factors, including oxidative stress. Psychotropic drugs of a chemical nature have demonstrated several side effects that elevated the impact of those illnesses. Faced with this situation, natural products appear to be a promising alternative. The aim of this study was to evaluate the anxiolytic and antidepressant effects of the

Indexed as

AnimalsAnti-Anxiety AgentsAntidepressive AgentsAntioxidantsAnxietyBehavior, AnimalBiphenyl CompoundsDepressionDisease Models, AnimalDose-Response Relationship, DrugMaze LearningPetroselinumPicratesPlant ExtractsPolyphenolsRats1,1-diphenyl-2-picrylhydrazylAnti-Anxiety AgentsAntidepressive AgentsAntioxidantsBiphenyl CompoundsPicratesPlant ExtractsPolyphenolsantidepressant-likeantioxidantanxiolyticherbal medicinenatural productsPetroselinum sativumpharmacologypolyphenol

Identifiers

PMID33916097
PMCPMC8037343
OpenAlexW3144756797

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.