Evidence map›Paper›PMID 33915912›Full record

ArticleInternational journal of molecular sciences2021

Magnetic Core-Shell Molecularly Imprinted Nano-Conjugates for Extraction of Antazoline and Hydroxyantazoline from Human Plasma-Material Characterization, Theoretical Analysis and Pharmacokinetics.

Joanna Giebułtowicz, Natalia Korytowska, Monika Sobiech, Sebastian Polak, Barbara Wiśniowska, Roman Piotrowski, Piotr Kułakowski, Piotr Luliński

Open access · goldAbstract readValidation Study
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
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  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Joanna GiebułtowiczDepartment of Bioanalysis and Drugs Analysis, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0002-2567-4453
Natalia KorytowskaDepartment of Bioanalysis and Drugs Analysis, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0001-8335-4469
Monika SobiechDepartment of Organic Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Sebastian PolakDepartment of Social Pharmacy, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.
Barbara WiśniowskaDepartment of Social Pharmacy, Faculty of Pharmacy, Jagiellonian University Medical College, Medyczna 9, 30-688 Kraków, Poland.ORCID 0000-0002-4740-7903
Roman PiotrowskiDepartment of Cardiology, Postgraduate Medical School, Grochowski Hospital, 04-073 Warsaw, Poland.ORCID 0000-0001-8034-4898
Piotr KułakowskiDepartment of Cardiology, Postgraduate Medical School, Grochowski Hospital, 04-073 Warsaw, Poland.
Piotr LulińskiDepartment of Organic Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0001-8421-5225
Medical University of Warsaw · PLGrochowski Hospital · PLJagiellonian University · PL

Funding

Ministerstwo Nauki i Szkolnictwa Wyższego 0305/DLG/2018/10
6 · The paper itself

Abstract

The aim of this study was to develop magnetic molecularly imprinted nano-conjugate sorbent for effective dispersive solid phase extraction of antazoline (ANT) and its metabolite, hydroxyantazoline (ANT-OH) in analytical method employing liquid chromatography coupled with mass spectrometry method. The core-shell material was characterized in terms of adsorption properties, morphology and structure. The heterogeneous population of adsorption sites towards ANT-OH was characterized by two K

Indexed as

AdsorptionAdultAntazolineHealthy VolunteersHumansMaleMolecularly Imprinted PolymersNanoconjugatesSolid Phase ExtractionAntazolineMolecularly Imprinted PolymersNanoconjugatesantazolineatrial fibrillationbiomedical applicationscore–shell nanostructuresdispersive solid phase extractionhydroxyantazolinemagnetic molecularly imprinted polymersmass spectrometryparticle characterization

Identifiers

PMID33915912
PMCPMC8038096
OpenAlexW3151621669

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.