Evidence map›Paper›PMID 33915898›Full record

ArticlePharmaceuticals (Basel, Switzerland)2021

MicroRNA-100 Mediates Hydrogen Peroxide-Induced Apoptosis of Human Retinal Pigment Epithelium ARPE-19 Cells.

Yuh-Shin Chang, Yo-Chen Chang, Po-Han Chen, Chia-Yang Li, Wen-Chuan Wu, Ying-Hsien Kao

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. CircMETTL3 Inhibits HJournal of ophthalmology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Immunomodulatory and Antioxidant Drugs in Glaucoma Treatment.Pharmaceuticals (Basel, Switzerland) · 2023
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yuh-Shin ChangChi Mei Medical Center, Department of Ophthalmology, Tainan 71004, Taiwan.ORCID 0000-0001-6247-5050
Yo-Chen ChangGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.
Po-Han ChenDepartment of Medical Research, E-Da Hospital, Kaohsiung 82445, Taiwan.
Chia-Yang LiGraduate Institute of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung 80708, Taiwan.ORCID 0000-0001-5689-9850
Wen-Chuan WuDepartment of Ophthalmology, China Medical University Hospital, Taichung 40402, Taiwan.
Ying-Hsien KaoDepartment of Medical Research, E-Da Hospital, Kaohsiung 82445, Taiwan.ORCID 0000-0001-7803-9384
Kaohsiung Medical University · TWE-Da Hospital · TWChina Medical University · TW

Funding

Chi-Mei Medical Center, Taiwan CMMOST10721E-Da Hospital EDAHT107039Kaohsiung Medical University Chung-Ho Memorial Hospital 107-7R48, 5T02Kaohsiung Municipal Ta-Tung Hospital 108-R02Ministry of Science and Technology, Taiwan MOST107-2314-B-384-009
6 · The paper itself

Abstract

This study investigated the regulatory role of microRNA 100 (miR-100) in hydrogen peroxide (H

Indexed as

heme oxygenase-1microRNA biosynthesismTORoxidative stresssignal transduction

Identifiers

PMID33915898
PMCPMC8067261
OpenAlexW3146822380

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.