Evidence map›Paper›PMID 33915782›Full record

ArticleLife (Basel, Switzerland)2021

Development of the Cerebrospinal Fluid in Early Stage after Hemorrhage in the Central Nervous System.

Petr Kelbich, Aleš Hejčl, Jan Krejsek, Tomáš Radovnický, Inka Matuchová, Jan Lodin, Jan Špička, Martin Sameš, Jan Procházka, Eva Hanuljaková and 1 more

Open access · goldAbstract read
In one paragraph

Article in Life (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Petr KelbichBiomedical Centre, Masaryk Hospital Ústí nad Labem, 401 13 Ústí nad Labem, Czech Republic.ORCID 0000-0002-9261-6827
Aleš HejčlDepartment of Neurosurgery, Masaryk Hospital Ústí nad Labem, J. E. Purkinje University, 401 13 Ústí nad Labem, Czech Republic.
Jan KrejsekDepartment of Clinical Immunology and Allergology, Faculty of Medicine and University Hospital in Hradec Králové, Charles University in Prague, 500 03 Hradec Králové, Czech Republic.
Tomáš RadovnickýDepartment of Neurosurgery, Masaryk Hospital Ústí nad Labem, J. E. Purkinje University, 401 13 Ústí nad Labem, Czech Republic.ORCID 0000-0003-3642-0448
Inka MatuchováBiomedical Centre, Masaryk Hospital Ústí nad Labem, 401 13 Ústí nad Labem, Czech Republic.
Jan LodinDepartment of Neurosurgery, Masaryk Hospital Ústí nad Labem, J. E. Purkinje University, 401 13 Ústí nad Labem, Czech Republic.
Jan ŠpičkaDepartment of Clinical Biochemistry, Masaryk Hospital Ústí nad Labem, 401 13 Ústí nad Labem, Czech Republic.
Martin SamešDepartment of Neurosurgery, Masaryk Hospital Ústí nad Labem, J. E. Purkinje University, 401 13 Ústí nad Labem, Czech Republic.
Jan ProcházkaDepartment of Anesthesiology, Perioperative Medicine and Intensive Care, Masaryk Hospital Ústí nad Labem, J. E. Purkinje University, 401 13 Ústí nad Labem, Czech Republic.
Eva HanuljakováBiomedical Centre, Masaryk Hospital Ústí nad Labem, 401 13 Ústí nad Labem, Czech Republic.
Petr VachataDepartment of Neurosurgery, Masaryk Hospital Ústí nad Labem, J. E. Purkinje University, 401 13 Ústí nad Labem, Czech Republic.
Charles University · CZKrajská Zdravotní · CZCzech Academy of Sciences, Institute of Experimental Medicine · CZ

Funding

Charles University in Prague, Faculty of Medicine in Hradec Králové, Czech Republic PROGRES Q40/10The Internal Grant of the Krajská zdravotní, a.s. in Ústí nad Labem, Czech Republic IGA-KZ-2019-1-7The Internal Grants of the Krajská zdravotní, a.s. in Ústí nad Labem, Czech Republic IGA-KZ-2020-1-7
6 · The paper itself

Abstract

Extravasation of blood in the central nervous system (CNS) represents a very strong damaged associated molecular patterns (DAMP) which is followed by rapid inflammation and can participate in worse outcome of patients. We analyzed cerebrospinal fluid (CSF) from 139 patients after the CNS hemorrhage. We compared 109 survivors (Glasgow Outcome Score (GOS) 5-3) and 30 patients with poor outcomes (GOS 2-1). Statistical evaluations were performed using the Wilcoxon signed-rank test and the Mann-Whitney U test. Almost the same numbers of erythrocytes in both subgroups appeared in days 0-3 (

Indexed as

aspartate aminotransferase in CSFcerebrospinal fluidCNS haemorrhagecoefficient of energy balanceerythrocytes in CSFinflammation in CNSneutrophils in CSFtotal protein in CSF

Identifiers

PMID33915782
PMCPMC8065782
OpenAlexW3146099806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.