Evidence map›Paper›PMID 33915746›Full record

ReviewJournal of clinical medicine2021

Application of Vibrational Spectroscopies in the Qualitative Analysis of Gingival Crevicular Fluid and Periodontal Ligament during Orthodontic Tooth Movement.

Fabrizia d'Apuzzo, Ludovica Nucci, Ines Delfino, Marianna Portaccio, Giuseppe Minervini, Gaetano Isola, Ismene Serino, Carlo Camerlingo, Maria Lepore

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Retrospective Descriptive Case Series on the Use of AMCOPBioengineering (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. New Approaches and Technologies in Orthodontics.Journal of clinical medicine · 2024
    Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Sensors (Basel, Switzerland) · 2022
    Article
  15. Observational
  16. Article
  17. Article
  18. Human Interleukin-1International journal of dentistry · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fabrizia d'ApuzzoMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, 80138 Napoli, Italy.ORCID 0000-0003-0291-9339
Ludovica NucciMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, 80138 Napoli, Italy.
Ines DelfinoDepartment of Ecological and Biological Sciences, University of Tuscia, 01100 Viterbo, Italy.
Marianna PortaccioDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Napoli, Italy.ORCID 0000-0003-4463-0779
Giuseppe MinerviniMultidisciplinary Department of Medical-Surgical and Dental Specialties, University of Campania Luigi Vanvitelli, 80138 Napoli, Italy.ORCID 0000-0002-8309-1272
Gaetano IsolaDepartment of General Surgery and Medical-Surgical Specialties, University of Catania, 95124 Catania, Italy.ORCID 0000-0003-4267-6992
Ismene SerinoDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Napoli, Italy.
Carlo CamerlingoCNR-SPIN, SuPerconductivity and Other INnovative Materials and Devices Institute, 80078 Pozzuoli, Italy.
Maria LeporeDepartment of Experimental Medicine, University of Campania Luigi Vanvitelli, 80138 Napoli, Italy.ORCID 0000-0003-2743-5904

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optical vibrational techniques show a high potentiality in many biomedical fields for their characteristics of high sensitivity in revealing detailed information on composition, structure, and molecular interaction with reduced analysis time. In the last years, we have used these techniques for investigating gingival crevicular fluid (GCF) and periodontal ligament (PDL) during orthodontic tooth treatment. The analysis with Raman and infrared signals of GCF and PDL samples highlighted that different days of orthodontic force application causes modifications in the molecular secondary structure at specific wavenumbers related to the Amide I, Amide III, CH deformation, and CH

Indexed as

gingival crevicular fluidinfrared spectroscopiesorthodontic tooth movementperiodontal ligamentRaman spectroscopiesvibrational spectroscopies

Identifiers

PMID33915746
PMCPMC8036342

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.