Evidence map›Paper›PMID 33915721›Full record

ReviewAnimals : an open access journal from MDPI2021

Zinc in Dog Nutrition, Health and Disease: A Review.

Ana Margarida Pereira, Margarida R G Maia, António José Mira Fonseca, Ana Rita Jordão Cabrita

Open access · goldAbstract readReview
In one paragraph

Review in Animals : an open access journal from MDPI, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 37 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Oral Supplementation ofAnimals : an open access journal from MDPI · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Molecular Biomarkers of Canine Reproductive Functions.Current issues in molecular biology · 2024
    Review
  13. Article
  14. Review
  15. Zinc Concentration in Blood Serum of Healthy Dogs.Biological trace element research · 2023
    Article
  16. Article
  17. Nutritional Composition and Untargeted Metabolomics Reveal the Potential ofAnimals : an open access journal from MDPI · 2022
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Ana Margarida PereiraLAQV, REQUIMTE, Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, R. Jorge Viterbo Ferreira nº 228, 4050-313 Porto, Portugal.ORCID 0000-0002-0179-3044
Margarida R G MaiaLAQV, REQUIMTE, Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, R. Jorge Viterbo Ferreira nº 228, 4050-313 Porto, Portugal.ORCID 0000-0002-1716-6205
António José Mira FonsecaLAQV, REQUIMTE, Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, R. Jorge Viterbo Ferreira nº 228, 4050-313 Porto, Portugal.ORCID 0000-0001-6237-417X
Ana Rita Jordão CabritaLAQV, REQUIMTE, Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, R. Jorge Viterbo Ferreira nº 228, 4050-313 Porto, Portugal.
Universidade do Porto · PT

Funding

Fundação para a Ciência e Tecnologia (FCT) DL 57/2016 - Norma transitóriaFundação para a Ciência e Tecnologia (FCT) PD/BDE/114427/2016Fundação para a Ciência e Tecnologia (FCT) UIDB/50006/2020
6 · The paper itself

Abstract

Zinc is an essential trace element, required for enzymatic, structural, and regulatory functions. As body reserves are scarce, an adequate zinc status relies on proper dietary supply and efficient homeostasis. Several biomarkers have been proposed that enable the detection of poor zinc status, but more sensitive and specific ones are needed to detect marginal deficiencies. The zinc content of commercial dry dog foods has great variability, with a more frequent non-compliance with the maximum authorized limit than with the nutritional requirement. The bioavailability of dietary zinc also plays a crucial role in ensuring an adequate zinc status. Despite controversial results, organic zinc sources have been considered more bioavailable than inorganic sources, albeit the zinc source effect is more evident after a restriction period of dietary zinc. Many disorders have been associated with inadequate zinc status, not being clear whether the occurrence of the disease is the consequence or the cause. This review presents data on zinc requirements and biomarkers for zinc status, that can be applied for the development of supplementation strategies of zinc in complete pet foods. Moreover, it provides an understanding of the role zinc plays in the health of dogs, and how altered zinc status affects diseases in dogs.

Indexed as

bioavailabilitybiomarkersdogrequirementszinczinc status-disorders

Identifiers

PMID33915721
PMCPMC8066201
OpenAlexW3146876067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.