Evidence map›Paper›PMID 33915473›Full record

ArticleJournal of biomechanics2021

Multiscale characterization of ovariectomized rat femur.

Jie Liu, Eun Kyoung Kim, Ai Ni, Yong-Rak Kim, Fengyuan Zheng, Beth S Lee, Do-Gyoon Kim

Abstract read
In one paragraph

Article in Journal of biomechanics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Repeated social defeat causes bone loss from mouse femur.Brain, behavior, & immunity - health · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jie LiuDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA; Division of Restorative Science and Prosthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
Eun Kyoung KimDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA.
Ai NiDivision of Biostatistics, College of Public Health, The Ohio State University, Columbus, OH, USA.
Yong-Rak KimZachry Department of Civil & Environmental Engineering, Texas A&M University, College Station, TX, USA.
Fengyuan ZhengDivision of Restorative Science and Prosthodontics, College of Dentistry, The Ohio State University, Columbus, OH, USA.
Beth S LeeDepartment of Physiology and Cell Biology, College of Medicine, The Ohio State University, Columbus, OH 43210, USA.
Do-Gyoon KimDivision of Orthodontics, College of Dentistry, The Ohio State University, Columbus, OH 43210, USA. Electronic address: kim.2508@osu.edu.

Funding

Viscoelastic deformation of bone matrix in postmenopauseR21AG033714 · NIA · OHIO STATE UNIVERSITY · PI KIM, DO-GYOON · 2009 to 2010
$334k
NIA NIH HHS R21 AG033714
6 · The paper itself

Abstract

Estrogen deficiency activates bone resorbing cells (osteoclasts) and to a lesser extent bone forming cells (osteoblasts), resulting in a gap between resorption and formation that leads to a net loss of bone. These cell activities alter bone architecture and tissue composition. Thus, the objective of this study is to examine whether multiscale (10

Indexed as

Bone DensityFemurAnimalsFemaleHumansOvariectomyRatsRats, Sprague-DawleyX-Ray MicrotomographyBone micro-CTEstrogenMatrix mineralizationNanoindentationOsteoporosis

Identifiers

PMID33915473
PMCPMC8166321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.