Evidence map›Paper›PMID 33915101›Full record

ReviewThe lancet. HIV2021

Overview of SARS-CoV-2 infection in adults living with HIV.

Juan Ambrosioni, José Luis Blanco, Juliana M Reyes-Urueña, Mary-Ann Davies, Omar Sued, Maria Angeles Marcos, Esteban Martínez, Silvia Bertagnolio, Jose Alcamí, Jose M Miro and 1 more

Open access · bronzeAbstract readReview
In one paragraph

Review in The lancet. HIV, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 117 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 3 pooled it
12.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 3 syntheses or guidelines pooled it, 220 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
  4. Trial
  5. Observational
  6. Article
  7. Article
  8. Article
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  11. A Pilot Study of COVID-19 Outcomes in People Living with HIV in Tatarstan.International journal of molecular sciences · 2025
    Article
  12. Review
  13. Review
  14. Article
  15. Observational
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 8 institutions in 5 countries.

Juan AmbrosioniInfectious Diseases Service, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain. Electronic address: jambrosioni@intramed.net.
José Luis BlancoInfectious Diseases Service, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
Juliana M Reyes-UrueñaCentre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya (CEEISCAT), Agència de Salut Pública de Catalunya, Barcelona, Spain; CIBER Epidemiologia y Salud Pública (CIBERESP), Madrid, Spain.
Mary-Ann DaviesCentre for Infectious Disease Epidemiology and Research, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa.
Omar SuedFundación Huésped, Buenos Aires, Argentina.
Maria Angeles MarcosMicrobiology Service, Hospital Clinic-ISGlobal, University of Barcelona, Barcelona, Spain.
Esteban MartínezInfectious Diseases Service, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain.
Silvia BertagnolioDepartment of Global HIV, Hepatitis, and STI Programmes, World Health Organization, Geneva, Switzerland; Department of Infection and Population Health, University College London, London, UK.
Jose AlcamíInfectious Diseases Service, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain; AIDS Immunopathogenesis Unit, Instituto de Salud Carlos III, Madrid, Spain.
Jose M MiroInfectious Diseases Service, Hospital Clinic-IDIBAPS, University of Barcelona, Barcelona, Spain. Electronic address: jmmiro@ub.edu.
COVID-19 in HIV Investigators
Consorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESUniversitat de Barcelona · ESAgència de Salut Pública de Catalunya · ESBarcelona Institute for Global Health · ESFundación Huésped · ARUniversity College London · GBUniversity of Cape Town · ZAWorld Health Organization · CH

Funding

World Health Organization 001
6 · The paper itself

Abstract

Around 2·5 million deaths and more than 110 million COVID-19 cases have been reported globally. Although it initially appeared that HIV infection was not a risk factor for COVID-19 or more severe disease, more recent large studies suggest that people living with HIV (particularly with low CD4 cell counts or untreated HIV infection) might have a more severe clinical course than those who are HIV-negative. Moreover, the COVID-19 pandemic has disrupted HIV prevention and treatment services worldwide, creating huge challenges to the continuity of essential activities. We have reviewed the most relevant features of COVID-19 in people living with HIV and highlighted topics where further research is required.

Indexed as

SARS-CoV-2Adaptive ImmunityComorbidityCOVID-19COVID-19 VaccinesDisease ProgressionFemaleHIV InfectionsHumansMalePrognosisCOVID-19 Vaccines

Identifiers

PMID33915101
PMCPMC8075775
OpenAlexW3158010736

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.