Evidence map›Paper›PMID 33915076›Full record

ArticleEmerging infectious diseases2021

Serotype-Switch Variant of Multidrug-Resistant Streptococcus pneumoniae Sequence Type 271.

Erin M Scherer, Bernard Beall, Benjamin Metcalf

Abstract read
In one paragraph

Article in Emerging infectious diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Ultrastructural, metabolic and genetic characteristics of determinants facilitating the acquisition of macrolide resistance by Streptococcus pneumoniae.Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy · 2024
    Article
  4. Article
  5. Molecular Epidemiology ofPathogens (Basel, Switzerland) · 2023
    Article
  6. Genomic Epidemiology ofPathogens (Basel, Switzerland) · 2023
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Erin M Scherer
Bernard Beall
Benjamin Metcalf

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We discovered 3 invasive, multidrug-resistant Streptococcus pneumoniae isolates of vaccine-refractory capsular serotype 3 that recently arose within the successful sequence type 271 complex through a serotype switch recombination event. Mapping genomic recombination sites within the serotype 3/sequence type 271 progeny revealed a 55.9-kb donated fragment that encompassed cps3, pbp1a, and additional virulence factors.

Indexed as

Pneumococcal InfectionsStreptococcus pneumoniaeAnti-Bacterial AgentsHumansMicrobial Sensitivity TestsPneumococcal VaccinesSerogroupSerotypingAnti-Bacterial AgentsPneumococcal Vaccinesantimicrobial resistancebacteriacapsular switchpneumococcalpneumococcusrecombinationrespiratory infectionsserotype 3ST271 lineagestreptococciStreptococcus pneumoniaevaccines

Identifiers

PMID33915076
PMCPMC8153891

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.