Evidence map›Paper›PMID 33914774›Full record

ArticlePloS one2021

MR. Estimator, a toolbox to determine intrinsic timescales from subsampled spiking activity.

F P Spitzner, J Dehning, J Wilting, A Hagemann, J P Neto, J Zierenberg, V Priesemann

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Recovery from disorders of consciousness: Lesions and GABAergic modulation in a biologically inspired spiking neural network.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Microscale Neuronal Activity Collectively Drives Chaotic and Inflexible Dynamics at the Macroscale in Seizures.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  7. Review
  8. Addressing skepticism of the critical brain hypothesis.Frontiers in computational neuroscience · 2022
    Review
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

F P SpitznerMax-Planck-Institute for Dynamics and Self-Organization, Göttingen, Germany.ORCID 0000-0001-9774-4572
J DehningMax-Planck-Institute for Dynamics and Self-Organization, Göttingen, Germany.
J WiltingMax-Planck-Institute for Dynamics and Self-Organization, Göttingen, Germany.
A HagemannMax-Planck-Institute for Dynamics and Self-Organization, Göttingen, Germany.
J P NetoMax-Planck-Institute for Dynamics and Self-Organization, Göttingen, Germany.
J ZierenbergMax-Planck-Institute for Dynamics and Self-Organization, Göttingen, Germany.ORCID 0000-0001-5840-3791
V PriesemannMax-Planck-Institute for Dynamics and Self-Organization, Göttingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here we present our Python toolbox "MR. Estimator" to reliably estimate the intrinsic timescale from electrophysiologal recordings of heavily subsampled systems. Originally intended for the analysis of time series from neuronal spiking activity, our toolbox is applicable to a wide range of systems where subsampling-the difficulty to observe the whole system in full detail-limits our capability to record. Applications range from epidemic spreading to any system that can be represented by an autoregressive process. In the context of neuroscience, the intrinsic timescale can be thought of as the duration over which any perturbation reverberates within the network; it has been used as a key observable to investigate a functional hierarchy across the primate cortex and serves as a measure of working memory. It is also a proxy for the distance to criticality and quantifies a system's dynamic working point.

Indexed as

Action PotentialsNeuronsAlgorithmsAnimalsHumansModels, NeurologicalSoftwareTime Factors

Identifiers

PMID33914774
PMCPMC8084202

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.