ArticlePLoS neglected tropical diseases2021
Routine deworming during antenatal care decreases risk of neonatal mortality and low birthweight: A retrospective cohort of survey data.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
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Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Systematic review to evaluate a potential association between helminth infection and physical stunting in children.Parasites & vectors · 2022Pooled it
- Effect of completing eight or more antenatal care contacts on adverse pregnancy outcomes in a district hospital in Ghana: A propensity score-matched and doubly robust analysis.Global epidemiology · 2026Article
- Determinants and regional inequalities in pregnancy deworming uptake in Somalia: findings from the 2020 Somalia demographic and health survey.IJID regions · 2026Article
- Determinants of uptake of deworming medication during pregnancy in Tanzania: insights from 2022 demographic and health survey.Journal of health, population, and nutrition · 2025Article
- Trends and inequalities in the use of deworming medication during pregnancy in Sierra Leone, 2008-2019.Tropical medicine and health · 2024Article
- Preterm birth, low birth weight, and their co-occurrence among women with preexisting chronic diseases prior to conception: a cross-sectional analysis of postpartum women in a low-resource setting in Ghana.Maternal health, neonatology and perinatology · 2024Article
- Communities' knowledge, perceptions and preventive practices on soil-transmitted helminthes in Jimma, Oromia, Ethiopia: Formative mixed study.PLoS neglected tropical diseases · 2024Article
- Decreased Weight-for-Age Associated with Mass Deworming among Young Ethiopian Schoolchildren in Jimma Town, Southwest Ethiopia: A School-Based Cross-Sectional Study.The American journal of tropical medicine and hygiene · 2024Article
- Disparities in health and nutrition between semi-urban and rural mothers and birth outcomes of their newborns in Bukavu, DR Congo: a baseline assessment.Primary health care research & development · 2023Article
- Mapping the quality of prenatal and postnatal care and demographic differences on child mortality in 26 low to middle-income countries.World journal of pediatrics : WJP · 2023Article
- Factors Associated with Deworming Medication Utilization among Pregnant Women in Benin: Evidence from the Demographic and Health Survey.Tropical medicine and infectious disease · 2023Article
- Iron supplementation and deworming during pregnancy reduces the risk of anemia and stunting in infants less than 2 years of age: a study from Sub-Saharan Africa.BMC pregnancy and childbirth · 2023Article
- Deworming utilization among pregnant mothers with at least one antenatal care follow-up in Ethiopia, 2022:- A multilevel analysis.PloS one · 2023Article
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- Malaria in pregnancy control and pregnancy outcomes: a decade's overview using Ghana's DHIMS II data.Malaria journal · 2022Review
- Individual and community level predictors of utilization of deworming medications among pregnant women in Ethiopia: A multilevel analysis.PLoS neglected tropical diseases · 2022Article
- Community-level impacts of sanitation coverage on maternal and neonatal health: a retrospective cohort of survey data.BMJ global health · 2021Article
- Utilization of deworming medication and its associated factors among pregnant married women in 26 sub-Saharan African countries: a multi-country analysis.Tropical medicine and health · 2021Article
- Utilization of Deworming Drugs and Its Individual and Community Level Predictors among Pregnant Married Women in Cameroon: A Multilevel Modeling.BioMed research international · 2021Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
Abstract
backgroundSoil transmitted helminths (STH) are a common infection among pregnant women in areas with poor access to sanitation. Deworming medications are cheap and safe; however, the health benefit of deworming during pregnancy is not clear. METHODS / PRINCIPAL
findingsWe created a retrospective cohort of more than 800,000 births from 95 Demographic and Health Survey datasets to estimate the impact of deworming medicine during routine antenatal care (ANC) on neonatal mortality and low birthweight. We first matched births on the probability of receiving deworming during ANC. We then modeled the birth outcomes with the matched group as a random intercept to estimate the effect of deworming during antenatal care after accounting for various risk factors. We also tested for effect modification of soil transmitted helminth prevalence on the impact of deworming during ANC. Receipt of deworming medication during ANC was associated with a 14% reduction in the risk of neonatal mortality (95% confidence interval = 10-17%, n = 797,772 births), with no difference between high and low transmission countries. In low transmission countries, we found an 11% reduction in the odds of low birth weight (95% confidence interval = 8-13%) for women receiving deworming medicine, and in high transmission countries, we found a 2% reduction in the odds of low birthweight (95% confidence interval = 0-5%). CONCLUSIONS / SIGNIFICANCE: These results suggest a substantial health benefit for deworming during ANC that may be even greater in countries with low STH transmission.
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