Evidence map›Paper›PMID 33914612›Full record

ArticleThe British journal of radiology2021

Safely achieving single prolonged breath-holds of > 5 minutes for radiotherapy in the prone, front crawl position.

M J Parkes, Wilfried De Neve, Vincent Vakaet, Geoffrey Heyes, Timothy Jackson, Richard Delaney, Gavin Kirby, Stuart Green, Warren Kilby, Jason Cashmore and 2 more

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Trial
  2. Prolonging breath-hold duration in radiotherapy using cognitive engagement.Clinical and translational radiation oncology · 2027
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

M J ParkesSchool of Sport, Exercise & Rehabilitation Sciences, Birmingham, UK.
Wilfried De NeveDepartment of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Vincent VakaetDepartment of Human Structure and Repair, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium.
Geoffrey HeyesHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Timothy JacksonHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Richard DelaneyHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Gavin KirbyHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Stuart GreenHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Warren KilbyAccuray Incorporated, Sunnyvale, CA, USA.
Jason CashmoreHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Qamar GhafoorHall Edwards Radiotherapy Group, University Hospitals Birmingham NHS Foundation Trust, Birmingham, UK.
Thomas Clutton-BrockNational Institute for Health Research (NIHR)/Wellcome Trust Birmingham Clinical Research Facility, Birmingham, UK.
University Hospitals Birmingham NHS Foundation Trust · GBGhent University · BEAcademic Medical Center · NLAccuray (United States) · USUniversity of Birmingham · GB

Funding

Wellcome Trust
6 · The paper itself

Abstract

objectiveBreast cancer radiotherapy is increasingly delivered supine with multiple, short breath-holds. There may be heart and lung sparing advantages for locoregional breast cancer of both prone treatment and in a single breath-hold. We test here whether single prolonged breath-holds are possible in the prone, front crawl position.

methods19 healthy volunteers were trained to deliver supine, single prolonged breath-holds with pre-oxygenation and hypocapnia. We tested whether all could achieve the same durations in the prone, front crawl position.

results19 healthy volunteers achieved supine, single prolonged breath-holds for mean of 6.2 ± 0.3 min. All were able to hold safely for the same duration while prone (6.1 ± 0.2 min

conclusionSingle prolonged (>5 min) breath-holds are equally possible in the prone, front crawl position. ADVANCES IN KNOWLEDGE: Prolonged breath-holds in the front crawl position are possible and have the same durations as in the supine position. Such training would therefore be feasible for some patients with breast cancer requiring loco-regional irradiation. It would have obvious advantages for hypofractionation.

Indexed as

Breath HoldingPatient SafetyProne PositionAdultBreast NeoplasmsFemaleHealthy VolunteersHumansSupine PositionTime Factors

Identifiers

PMID33914612
PMCPMC8173692
OpenAlexW3157509081

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.