Evidence map›Paper›PMID 33914282›Full record

SynthesisSports medicine (Auckland, N.Z.)2021

The Effect of Impact Exercise (Alone or Multicomponent Intervention) on Health-Related Outcomes in Individuals at Risk of Fractures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Isabel B Rodrigues, Matteo Ponzano, Zeinab Hosseini, Lehana Thabane, Philip D Chilibeck, Debra A Butt, Maureen C Ashe, Jackie Stapleton, John Wark, Lora M Giangregorio

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Sports medicine (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Clinical practice guideline for management of osteoporosis and fracture prevention in Canada: 2023 update.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Guideline
  3. Approach to personalizing the treatment of osteoporosis.The Journal of clinical endocrinology and metabolism · 2026
    Review
  4. Article
  5. Among people on osteoporosis medication, loss of appendicular or total body lean mass is an independent risk factor for hip and major osteoporotic fractures.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2024
    Article
  6. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023
    Article
  7. Strength-training and balance activities in Canada: historical trends and current prevalence.Health promotion and chronic disease prevention in Canada : research, policy and practice · 2023
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Isabel B RodriguesDepartment of Kinesiology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.ORCID http://orcid.org/0000-0002-3158-813X
Matteo PonzanoDepartment of Kinesiology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
Zeinab HosseiniCollege of Kinesiology, University of Saskatchewan, Saskatoon, SK, S7N 5B2, Canada.
Lehana ThabaneDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Philip D ChilibeckCollege of Kinesiology, University of Saskatchewan, Saskatoon, SK, S7N 5B2, Canada.
Debra A ButtDepartment of Family and Community Medicine, University of Toronto, Toronto, ON, M5G 1V7, Canada.
Maureen C AsheDepartment of Family Practice, University of British Columbia, Vancouver, BC, V6T 1Z3, Canada.ORCID http://orcid.org/0000-0002-6820-4435
Jackie StapletonUniversity of Waterloo Library, University of Waterloo, Waterloo, ON, N2L 3G1, Canada.
John WarkDepartment of Medicine, Bone and Mineral Medicine, Department of Diabetes and Endocrinology, University of Melbourne, Royal Melbourne Hospital, Victoria, 3050, Australia.
Lora M GiangregorioDepartment of Kinesiology, University of Waterloo, Waterloo, ON, N2L 3G1, Canada. lora.giangregorio@uwaterloo.ca.

Funding

Institute of Musculoskeletal Health and Arthritis CIHR Doctoral Award
6 · The paper itself

Abstract

backgroundExercise is commonly recommended to prevent and manage osteoporosis. High magnitude strains at rapid rate and short bouts should theoretically elicit an osteogenic response; however, the effects of different levels of impact exercises on several outcomes in people at risk of fracture are still unknown.

objectiveTo report the effect of impact exercise on falls, fractures, adverse events, mortality, bone mineral density (BMD), physical functioning, and health-related quality of life (QoL).

methodsWe included randomized controlled trials testing the effect of impact exercise compared with a non-exercise control on outcomes in adults ≥ 50 years with low BMD or fragility fractures. Two reviewers selected studies and extracted data. Where possible, we pooled outcomes using mean difference (MD) with a fixed-effects model and 95% confidence interval (CI). We reported risk of bias using Cochrane and certainty of evidence using GRADE.

resultsWe included 29 trials; 19 studies evaluated impact exercise alone, and the remaining trials combined impact with resistance or balance training. Impact exercise alone or combined with resistance training improved Timed Up-and-Go values (MD - 0.95 s, 95% CI - 1.09 to - 0.81, low certainty evidence) and lumbar spine (MD 0.04 g/cm

conclusionsThere is low certainty evidence that impact exercise may improve physical function and BMD in people at risk of fracture. The effect of impact exercises on falls, fractures, and mortality remains unclear. Our findings should be interpreted with caution due to risk of bias and small sample sizes.

trial registrationRegistered in Prospero (CRD42018115579) on January 30, 2019.

Indexed as

Fractures, BoneQuality of LifeAdultExerciseExercise TherapyHumansRandomized Controlled Trials as Topic

Identifiers

PMID33914282

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.