Evidence map›Paper›PMID 33914222›Full record

ArticleMetabolic brain disease2021

Sexual dimorphism in rats exposed to maternal high fat diet: alterations in medullary sympathetic network.

Ayşegül Gemici, Osman Sinen, Mehmet Bülbül

Abstract read
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In one paragraph

Article in Metabolic brain disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Ayşegül GemiciDepartment of Physiology, Faculty of Medicine, Akdeniz University, 07070, Antalya, Turkey.
Osman SinenDepartment of Physiology, Faculty of Medicine, Akdeniz University, 07070, Antalya, Turkey.ORCID http://orcid.org/0000-0002-3554-5604
Mehmet BülbülDepartment of Physiology, Faculty of Medicine, Akdeniz University, 07070, Antalya, Turkey. mehmetbulbul@akdeniz.edu.tr.ORCID http://orcid.org/0000-0002-2093-6178
Akdeniz University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure to high fat diet during perinatal period (PHFD) leads to neuroplastic changes in autonomic circuits, however, the role of gender has been incompletely understood. This study aims to investigate (i) short, and (ii) long-term effects of PHFD on autonomic outflow, and (iii) sexual dimorphic variations emerge at adulthood. Male and female rats were fed a control diet (13.5 % kcal from fat) or PHFD (60 % kcal from fat) from embryonic day-14 to postnatal day-21. To assess changes in autonomic outflow, heart rate variability (HRV) was analyzed at 10- and 20-week-old ages. Expressions of tyrosine hydroxylase (TH), metabotropic glutamate

Indexed as

Diet, High-FatMaternal ExposureSex CharacteristicsAdrenergic beta-AntagonistsAnimalsAnimals, NewbornBody WeightFemaleHeart RateMaleMedulla OblongataNerve NetPregnancyPrenatal Exposure Delayed EffectsPropranololRatsAdrenergic beta-AntagonistsPropranololReceptors, GABAReceptors, N-Methyl-D-AspartateGenderHeart rate variabilityPerinatal high fat dietSympathetic tone

Identifiers

PMID33914222
OpenAlexW3157605207

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.