Evidence map›Paper›PMID 33914141›Full record

ArticleJournal of neurology2021

Intraluminal carotid thrombosis and acute ischemic stroke associated with COVID-19.

Diaa Hamouda, Dinesh V Jillella, Nirav Bhatt, Sitara Koneru, Michael R Frankel, Raul G Nogueira

Open access · bronzeAbstract read
In one paragraph

Article in Journal of neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 6 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Diaa HamoudaDepartment of Neurology, Emory University School of Medicine and Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA.
Dinesh V JillellaDepartment of Neurology, Emory University School of Medicine and Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA. dineshvinayakjillella@gmail.com.ORCID http://orcid.org/0000-0002-5399-0170
Nirav BhattDepartment of Neurology, Emory University School of Medicine and Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA.
Sitara KoneruDepartment of Neurology, Emory University School of Medicine and Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA.
Michael R FrankelDepartment of Neurology, Emory University School of Medicine and Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA.
Raul G NogueiraDepartment of Neurology, Emory University School of Medicine and Marcus Stroke and Neuroscience Center, Grady Memorial Hospital, Atlanta, GA, USA.
Grady Memorial Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

COVID-19 (Coronavirus disease 2019) caused by SARS-CoV-2 has a diverse constellation of neurological manifestations that include encephalopathy, stroke, Guillain-Barré syndrome, myelitis, and encephalitis. Intraluminal carotid thrombi (ILT) are infrequent lesions seen in only 1.6% of patients with acute ischemic stroke. Underlying atherosclerosis is the most common lesion associated with ILT formation. However, with COVID-19, we have encountered ILT in patients without significant atherosclerotic disease. The endothelial inflammation and hypercoagulable state associated with COVID-19 pose a risk of arterial and venous thromboembolism and could have contributed to this presentation although the exact pathophysiology and optimal treatment of ILT in COVID-19 remain elusive. Herein, we present a series of ischemic stroke patients with carotid ILT in the setting of a recent SARS-CoV-2 infection.

Indexed as

Brain IschemiaCarotid Artery ThrombosisCOVID-19Ischemic StrokeStrokeHumansSARS-CoV-2Acute strokeCarotid thrombusCOVID-19Intraluminal thrombusIschemic stroke

Identifiers

PMID33914141
PMCPMC8082747
OpenAlexW3159475931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.