Evidence map›Paper›PMID 33914136›Full record

ReviewApplied microbiology and biotechnology2021

Synthesis and production of steviol glycosides: recent research trends and perspectives.

Marta Libik-Konieczny, Ewa Capecka, Monika Tuleja, Robert Konieczny

Open access · hybridAbstract readReview
In one paragraph

Review in Applied microbiology and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 80 citations in OpenAlex.

  1. The dual role of polyethylene glycol-simulated drought stress inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2026
    Review
  2. Article
  3. Review
  4. Article
  5. Invasive Asian water moss (Frontiers in plant science · 2026
    Article
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  8. Review
  9. Article
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  14. The sugar donor specificity of plant family 1 glycosyltransferases.Frontiers in bioengineering and biotechnology · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Marta Libik-KoniecznyThe Franciszek Górski Institute of Plant Physiology, Polish Academy of Sciences, ul. Niezapominajek 21, 30-239, Krakow, Poland. libik@ifr-pan.krakow.pl.ORCID http://orcid.org/0000-0002-4787-4018
Ewa CapeckaDepartment of Horticulture, Faculty of Biotechnology and Agriculture, University of Agriculture in Krakow, al. 29 Listopada 54, 31-425, Kraków, Poland.
Monika TulejaDepartment of Plant Cytology and Embryology, Institute of Botany, Faculty of Biology, Jagiellonian University, ul. Gronostajowa 9, 30-387, Krakow, Poland.
Robert KoniecznyDepartment of Plant Cytology and Embryology, Institute of Botany, Faculty of Biology, Jagiellonian University, ul. Gronostajowa 9, 30-387, Krakow, Poland.
Jagiellonian University · PLFranciszek Górski Institute of Plant Physiology · PLUniversity of Agriculture in Krakow · PL

Funding

Narodowe Centrum Nauki 2012/05/B/NZ9/01035Narodowe Centrum Nauki 2013/09/N/NZ9/01650
6 · The paper itself

Abstract

Steviol glycosides (SvGls) are plant secondary metabolites belonging to a class of chemical compounds known as diterpenes. SvGls have been discovered only in a few plant species, including in the leaves of Stevia rebaudiana Bertoni. Over the last few decades, SvGls have been extensively researched for their extraordinary sweetness. As a result, the nutritional and pharmacological benefits of these secondary metabolites have grown increasingly apparent. In the near future, SvGls may become a basic, low-calorie, and potent sweetener in the growing natural foods market, and a natural anti-diabetic remedy, a highly competitive alternative to commercially available synthetic drugs. Commercial cultivation of stevia plants and the technologies of SvGls extraction and purification from plant material have already been introduced in many countries. However, new conventional and biotechnological solutions are still being sought to increase the level of SvGls in plants. Since many aspects related to the biochemistry and metabolism of SvGls in vivo, as well as their relationship to the overall physiology of S. rebaudiana are not yet understood, there is also a great need for in-depth scientific research on this topic. Such research may have positive impact on optimization of the profile and SvGls concentration in plants and thus lead to obtaining desired yield. This research summarizes the latest approaches and developments in SvGls production. KEY POINTS: • Steviol glycosides (SvGls) are found in nature in S. rebaudiana plants. • They exhibit nutraceutical properties. • This review provides an insight on different approaches to produce SvGls. • The areas of research that still need to be explored have been identified.

Indexed as

Diterpenes, KauraneSteviaGlucosidesGlycosidesPlant LeavesSweetening AgentsDiterpenes, KauraneGlucosidesGlycosidessteviosideSweetening AgentsBiotechnologyDiterpene glycosideSecondary metabolismStevia

Identifiers

PMID33914136
PMCPMC8140977
OpenAlexW3157378710

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.