ReviewJMIR mental health2021
Evidence on Digital Mental Health Interventions for Adolescents and Young People: Systematic Overview.
Review in JMIR mental health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06759441 (Exploring the Effectiveness of a Suicide Ideation Prevention Program), which is not on this map. Cited by 249 papers, 20 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exploring the Effectiveness of a Suicide Ideation Prevention Program: Reframe-IT+
Who cites it
249 citing papers in PubMed, 20 syntheses or guidelines pooled it.
- Self-administered single-session interventions for mental health in young people: A systematic review and meta-analysis.Journal of child psychology and psychiatry, and allied disciplines · 2026Pooled it
- Digital psychological interventions in youth with neurological disorders: a systematic review.Journal of pediatric psychology · 2026Pooled it
- Factors Influencing the Initiation and Continued Engagement of Digital Mental Health Tools Among Adults: Theory of Planned Behavior-Informed Systematic Review.JMIR mental health · 2026Pooled it
- Technology-Assisted Interventions for Reducing Risk of Suicide: A Meta-Analysis Focused on Suicidal Ideation.Actas espanolas de psiquiatria · 2026Pooled it
- Social-emotional competencies and health-related outcomes of health promotion in upper secondary education: a scoping review of German-speaking countries.Frontiers in psychology · 2026Pooled it
- The Efficacy of Rule-Based Versus Large Language Model-Based Chatbots in Alleviating Symptoms of Depression and Anxiety: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2025Pooled it
- Biofeedback-based Digital Games and Well-being in Childhood: A Systematic Review.Research on child and adolescent psychopathology · 2025Pooled it
- Updates on digital mental health interventions for children and young people: systematic overview of reviews.European child & adolescent psychiatry · 2025Pooled it
- Digital Mental Health Interventions for the Prevention and Treatment of Social Anxiety Disorder in Children, Adolescents, and Young Adults: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2025Pooled it
- Digital health interventions with healthcare information and self-management resources for young people with ADHD: a mixed-methods systematic review and narrative synthesis.European child & adolescent psychiatry · 2025Pooled it
- Planning, implementation, evaluation, and sustainment of digital health interventions for adolescent substance use prevention: a systematic review of influencing factors based on the RE-AIM framework.Health education research · 2025Pooled it
- Could the use of web-based applications assist in neuropsychiatric treatment? An umbrella review.BMC psychology · 2025Pooled it
- Digital Mental Health Interventions for University Students With Mental Health Difficulties: A Systematic Review and Meta-Analysis.Early intervention in psychiatry · 2025Pooled it
- Internet- and mobile-based anxiety and depression interventions for children and adolescents: efficacy and negative effects - a systematic review and meta-analysis.European child & adolescent psychiatry · 2025Pooled it
- Barriers to and facilitators of user engagement with web-based mental health interventions in young people: a systematic review.European child & adolescent psychiatry · 2025Pooled it
- The Acceptability, Engagement, and Feasibility of Mental Health Apps for Marginalized and Underserved Young People: Systematic Review and Qualitative Study.Journal of medical Internet research · 2024Pooled it
- Outcomes of Best-Practice Guided Digital Mental Health Interventions for Youth and Young Adults with Emerging Symptoms: Part II. A Systematic Review of User Experience Outcomes.Clinical child and family psychology review · 2024Pooled it
- Outcomes of Best-Practice Guided Digital Mental Health Interventions for Youth and Young Adults with Emerging Symptoms: Part I. A Systematic Review of Socioemotional Outcomes and Recommendations.Clinical child and family psychology review · 2024Pooled it
- The Effect of Digital Mental Health Literacy Interventions on Mental Health: Systematic Review and Meta-Analysis.Journal of medical Internet research · 2024Pooled it
- Mobile applications in adolescent psychotherapy during the COVID-19 pandemic: a systematic review.Frontiers in public health · 2024Pooled it
189 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn estimated 1 in 5 adolescents experience a mental health disorder each year; yet because of barriers to accessing and seeking care, most remain undiagnosed and untreated. Furthermore, the early emergence of psychopathology contributes to a lifelong course of challenges across a broad set of functional domains, so addressing this early in the life course is essential. With increasing digital connectivity, including in low- and middle-income countries, digital health technologies are considered promising for addressing mental health among adolescents and young people. In recent years, a growing number of digital health interventions, including more than 2 million web-based mental health apps, have been developed to address a range of mental health issues.
objectiveThis review aims to synthesize the current evidence on digital health interventions targeting adolescents and young people with mental health conditions, aged between 10-24 years, with a focus on effectiveness, cost-effectiveness, and generalizability to low-resource settings (eg, low- and middle-income countries).
methodsWe searched MEDLINE, PubMed, PsycINFO, and Cochrane databases between January 2010 and June 2020 for systematic reviews and meta-analyses on digital mental health interventions targeting adolescents and young people aged between 10-24 years. Two authors independently screened the studies, extracted data, and assessed the quality of the reviews.
resultsIn this systematic overview, we included 18 systematic reviews and meta-analyses. We found evidence on the effectiveness of computerized cognitive behavioral therapy on anxiety and depression, whereas the effectiveness of other digital mental health interventions remains inconclusive. Interventions with an in-person element with a professional, peer, or parent were associated with greater effectiveness, adherence, and lower dropout than fully automatized or self-administered interventions. Despite the proposed utility of digital interventions for increasing accessibility of treatment across settings, no study has reported sample-specific metrics of social context (eg, socioeconomic background) or focused on low-resource settings.
conclusionsAlthough digital interventions for mental health can be effective for both supplementing and supplanting traditional mental health treatment, only a small proportion of existing digital platforms are evidence based. Furthermore, their cost-effectiveness and effectiveness, including in low- and middle-income countries, have been understudied. Widespread adoption and scale-up of digital mental health interventions, especially in settings with limited resources for health, will require more rigorous and consistent demonstrations of effectiveness and cost-effectiveness vis-à-vis the type of service provided, target population, and the current standard of care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.