Evidence map›Paper›PMID 33913402›Full record

ArticleJournal of histotechnology2021

The effect of ergot alkaloid exposure during gestation on the microscopic morphology and vasculature of the ovine placenta.

J L Britt, R R Powell, C McMahan, T F Bruce, S K Duckett

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of histotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Risks for animal health related to the presence of ergot alkaloids in feed.EFSA journal. European Food Safety Authority · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

J L BrittDepartment of Animal and Veterinary Sciences, Clemson University, Clemson, SC, USA.
R R PowellClemson Light Imaging Facility, Clemson University, Clemson, SC, USA.ORCID 0000-0001-5813-2610
C McMahanDepartment of Bioengineering, Clemson University, Clemson, SC, USA.
T F BruceClemson Light Imaging Facility, Clemson University, Clemson, SC, USA.ORCID 0000-0002-7672-4289
S K DuckettDepartment of Animal and Veterinary Sciences, Clemson University, Clemson, SC, USA.
Clemson University · US

Funding

The role of acetate fermentation in Entamoeba histolytica growth and infectionP20GM109094 · NIGMS · CLEMSON UNIVERSITY · PI MORRIS, MEREDITH T · 2016 to 2020
$10.4M
Transnational Research Imaging Core (TRI)P30GM131959 · NIGMS · CLEMSON UNIVERSITY · PI VYAVAHARE, NAREN R · 2019 to 2023
$5.9M
UNDERSTANDING AND CONTROLLING TISSUE-SPECIFIC VASCULAR PATTERNINGP20RR021949 · NCRR · CLEMSON UNIVERSITY · PI MARKWALD, ROGER R · 2009 to 2011
$5.2M
NCRR NIH HHS P20 RR021949NIGMS NIH HHS P20 GM109094NIGMS NIH HHS P30 GM131959
6 · The paper itself

Abstract

Ergot alkaloids, a class of mycotoxins associated with ergotism, act as agonists on serotonin (5HT) receptors, specifically 5HT2a, which mediate smooth muscle contraction and vasoconstriction. The objective of this study was to examine the impact of ergot alkaloid exposure during mid and late gestation on microscopic placental structure and vascular development. Ewes were fed endophyte-infected tall fescue seed containing ergot alkaloids (E+/E+, 1.77 mg ewe

Indexed as

Ergot AlkaloidsFestucaAnimalsEndophytesFemalePlacentaPregnancySheepSheep, DomesticErgot Alkaloidsergot alkaloidsplacental structureSheepvascular development

Identifiers

PMID33913402
PMCPMC8553796
OpenAlexW3158650517

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.