ArticleAnalytical and bioanalytical chemistry2021
Integrating high-performing electrochemical transducers in lateral flow assay.
Article in Analytical and bioanalytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Electrochemical Detection of SMN Protein by Immunosensors: The Role of Surface Modifications in Screen-Printed Carbon Electrodes.Sensors (Basel, Switzerland) · 2026Article
- Electrochemical lateral flow assay with ELISA-level performance for detecting plant diseases in East Africa.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Au-IDE/LFA biosensor: an integrated sensing platform with lateral flow immunoassay for quantitative detection of hCG hormone using non-faradaic continuous FFT-admittance voltammetry.BMC biotechnology · 2026Article
- Ultrasensitive electrochemical dipstick lateral flow immunoassay for extracellular vesicle quantification using starch-iodine functionalized gold nanoparticles.Mikrochimica acta · 2026Article
- A Printable OECT for Simple Integration in Nitrocellulose-Based Assays.ACS sensors · 2025Article
- Transitions in Immunoassay Leading to Next-Generation Lateral Flow Assays and Future Prospects.Biomedicines · 2024Review
- Lateral flow assays: Progress and evolution of recent trends in point-of-care applications.Materials today. Bio · 2024Review
- NFC Smartphone-Based Electrochemical Microfluidic Device Integrated with Nanobody Recognition for C-Reactive Protein.ACS sensors · 2024Article
- Nanomaterial-based Electrochemical Sensors for Multiplex Medicinal Applications.Current topics in medicinal chemistry · 2024Review
- Electrochemical Affinity Biosensors: Pervasive Devices with Exciting Alliances and Horizons Ahead.ACS sensors · 2023Review
- Review
- A Novel Sample-to-Answer Visual Nucleic Acid Detection System for Adenovirus Detection.Microbiology spectrum · 2023Article
- Aptamer-based CRISPR-Cas powered diagnostics of diverse biomarkers and small molecule targets.Applied biological chemistry · 2023Review
- Hybrid 3D printed integrated microdevice for the determination of copper ions in human body fluids.Analytical and bioanalytical chemistry · 2022Article
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lateral flow assays (LFAs) are the best-performing and best-known point-of-care tests worldwide. Over the last decade, they have experienced an increasing interest by researchers towards improving their analytical performance while maintaining their robust assay platform. Commercially, visual and optical detection strategies dominate, but it is especially the research on integrating electrochemical (EC) approaches that may have a chance to significantly improve an LFA's performance that is needed in order to detect analytes reliably at lower concentrations than currently possible. In fact, EC-LFAs offer advantages in terms of quantitative determination, low-cost, high sensitivity, and even simple, label-free strategies. Here, the various configurations of EC-LFAs published are summarized and critically evaluated. In short, most of them rely on applying conventional transducers, e.g., screen-printed electrode, to ensure reliability of the assay, and additional advances are afforded by the beneficial features of nanomaterials. It is predicted that these will be further implemented in EC-LFAs as high-performance transducers. Considering the low cost of point-of-care devices, it becomes even more important to also identify strategies that efficiently integrate nanomaterials into EC-LFAs in a high-throughput manner while maintaining their favorable analytical performance. Graphical abstract.
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