Evidence map›Paper›PMID 33912988›Full record

Observational studySurgical and radiologic anatomy : SRA2021

Femoral Intercondylar Notch: Gross Anatomy and Histology of the Connective Tissue Lining of its Roof: A Pilot Study.

Hira Lal Nag, Gunjar Jain, Vivek Vijayakumar, Tony George Jacob, Mukinkumar Sonai, Sanjeev Lalwani

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in Surgical and radiologic anatomy : SRA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Anatomical Tissue Engineering of the Anterior Cruciate Ligament Entheses.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Hira Lal NagDepartment of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India, 110049.ORCID http://orcid.org/0000-0001-6574-7840
Gunjar JainDepartment of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India, 110049. drgunjarjain@gmail.com.ORCID http://orcid.org/0000-0002-3458-189X
Vivek VijayakumarDepartment of Orthopaedics, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India, 110049.ORCID http://orcid.org/0000-0002-4716-6054
Tony George JacobDepartment of Anatomy, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India, 110029.ORCID http://orcid.org/0000-0003-1812-4805
Mukinkumar SonaiDepartment of Pathology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India, 110029.ORCID http://orcid.org/0000-0002-1441-8374
Sanjeev LalwaniDepartment of FMT, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India, 110029.ORCID http://orcid.org/0000-0001-7272-9579
All India Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe have consistently observed a connective tissue lining over the intercondylar notch's roof (CTLINR) during arthroscopic surgeries of the knee joint. As there is a strong association of the intercondylar fossa with the anterior cruciate ligament (ACL), we believe that this tissue must be having some role in the functioning of the ACL. The purpose of this pilot study was to investigate the anatomic characteristics of the CTLINR.

methodsIn this observational anatomical study, we have investigated the gross anatomical and histological features of the CTLINR in four knees of two fresh frozen non-embalmed cadavers. We have also studied its ultrastructural characteristics by obtaining an arthroscopic biopsy of the tissue from a patient undergoing ACL reconstruction.

resultsAt gross examination, the CTLINR had a typical glistening white surface with transversely oriented fibres. It entirely covered the roof of the intercondylar notch and was soft to touch. Histological examination with haematoxylin-eosin stain revealed fibro-collagenous tissue with intervening blood vessels. Transmission electron microscopy manifested loosely arranged collagen fibres of variable diameter.

conclusionThe histological and electron microscopic characteristics of the tissue differentiate it from the ACL and its femoral enthesis, suggesting that it was a distinct anatomical structure. As it entirely covered the roof of the intercondylar fossa and had a smooth surface and soft consistency, it may protect the reconstructed ACL from graft abrasion. Furthermore, as it had a characteristic arthroscopic appearance, future research can investigate its role in femoral tunnel positioning.

Indexed as

AdultFemaleFemurHumansKnee JointMaleMiddle AgedPilot ProjectsYoung AdultACLAnatomyAnterior cruciate ligamentConnective tissueHistologyIntercondylar Notch

Identifiers

PMID33912988
OpenAlexW3158092278

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.