ArticleCritical care explorations2021
Posttraumatic Stress Disorder Symptom Trajectories in ICU Family Caregivers.
Article in Critical care explorations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Determinants of caregiver burden among family caregivers of post-intensive care syndrome patients at 2 weeks post-discharge: a cross-sectional study.BMC nursing · 2026Article
- Risk Factors of Post-Traumatic Stress Disorder Symptom Trajectories for ICU Bereaved Family Members.Annals of the American Thoracic Society · 2025Article
- Social Support Mediates the 6-Month Mental Health-related Quality of Life of Intensive Care Unit Caregivers with Depressive Symptoms.Annals of the American Thoracic Society · 2024Article
- Association between hair cortisol concentration and acute stress symptoms in family members of critically ill patients: a cross-sectional study.Critical care science · 2024Article
- Comorbid Prolonged Grief, PTSD, and Depression Trajectories for Bereaved Family Surrogates.JAMA network open · 2023Article
- Posttraumatic Stress Symptom Trajectories in Family Caregivers of Patients With Acute Cardiorespiratory Failure.JAMA network open · 2023Article
- Posttraumatic Stress Disorder Symptom Clusters in Surrogate Decision Makers of Patients Experiencing Chronic Critical Illness.Critical care explorations · 2022Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
To use latent class growth analysis to identify posttraumatic stress disorder symptom trajectories in ICU family caregivers.
designProspective cohort study.
settingThe medical ICU at a tertiary-care center in the United States.
participantsAdult patients experiencing acute cardiorespiratory failure (defined as requiring at least one of the following: 1) vasopressors, 2) noninvasive positive pressure ventilation, 3) high-flow nasal cannula, or 4) mechanical ventilation) were enrolled in a pair with their primary family caregivers. MEASUREMENTS AND MAIN
resultsParticipants were enrolled within the first 48 hours of ICU admission. Family caregiver posttraumatic stress disorder symptoms were measured using the Impact of Events Scale-Revised at four time points: at enrollment, shortly after ICU discharge, and at 3 and 6 months after ICU discharge. The data were examined using latent class growth analysis to identify posttraumatic stress disorder symptom trajectories. Two distinct symptom trajectories were identified: a persistently high trajectory, characterized by high posttraumatic stress disorder symptoms at initial assessment, which remained elevated over time, and a persistently low trajectory, characterized by low posttraumatic stress disorder symptoms at initial assessment, which remained low over time. Approximately two-thirds of caregivers belonged to the persistently high trajectory, and one-third of caregivers belonged to the persistently low trajectory.
conclusionsUsing latent class growth analysis to measure 6-month ICU family caregiver posttraumatic stress disorder symptom trajectories, we identified two distinct trajectories (persistently low and persistently high). A larger cohort study is warranted to further delineate posttraumatic stress disorder trajectories in this population, with the ultimate goal of targeting high-risk caregivers for interventions to reduce psychologic distress and improve long-term caregiver outcomes.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.