Evidence map›Paper›PMID 33912579›Full record

ArticleFrontiers in medicine2021

Relationship of Soluble Interleukin-6 Receptors With Asthma: A Mendelian Randomization Study.

Yoshihiko Raita, Zhaozhong Zhu, Carlos A Camargo, Robert J Freishtat, Debby Ngo, Liming Liang, Kohei Hasegawa

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Review
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Yoshihiko RaitaDepartment of Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Zhaozhong ZhuDepartment of Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Carlos A CamargoDepartment of Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Robert J FreishtatDivision of Emergency Medicine, Children's National Hospital, Washington, DC, United States.
Debby NgoPulmonary, Critical Care and Sleep Medicine, Beth Israel Deaconess Medical Center, Boston, MA, United States.
Liming LiangProgram in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, United States.
Kohei HasegawaDepartment of Emergency Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.
Harvard University · USBeth Israel Deaconess Medical Center · USGeorge Washington University · USMassachusetts General Hospital · US

Funding

Airway dual-transcriptomics in bronchiolitis and risk of asthma: MARC-35 cohortR01AI137091 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2018 to 2022
$4.3M
Airway metagenome & metabolome in bronchiolitis and risk of asthma: MARC-35 cohortR01AI134940 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI HASEGAWA, KOHEI · 2018 to 2022
$4.0M
Infant blood epigenome and risks of IgE sensitization, obesity, and asthma: MARC-35/43 cohortsR01AI148338 · NIAID · HARVARD SCHOOL OF PUBLIC HEALTH · PI CAMARGO, CARLOS ARTURO, LIANG, LIMING · 2020 to 2023
$2.5M
Integrating the genome, metabolome, and microbiome for childhood asthma: Risk and endotypesK01AI153558 · NIAID · MASSACHUSETTS GENERAL HOSPITAL · PI ZHU, ZHAOZHONG · 2021 to 2025
$663k
Medical Research Council MC_PC_17228Medical Research Council MC_QA137853NIAID NIH HHS K01 AI153558NIAID NIH HHS R01 AI134940NIAID NIH HHS R01 AI137091NIAID NIH HHS R01 AI148338
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

asthmaGWASinterleukin-6Mendelian randomizationsoluble interleukin-6 receptortrans-signaling pathwayUK Biobank

Identifiers

PMID33912579
PMCPMC8071981
OpenAlexW3156888081

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.