Evidence map›Paper›PMID 33912469›Full record

ArticleFrontiers in oncology2021

Molecular and Clinical Insights in Malignant Brenner Tumor of the Testis With Liver Metastases:A Case Report.

Pietro Parcesepe, Luigi Coppola, Andrea Remo, Mario Rosario D'Andrea, Giulia Coppola, Michele Simbolo, Erminia Manfrin, Aldo Scarpa, Elena De Santis, Guido Giordano

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Pietro ParcesepeSection of Pathology, Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.
Luigi CoppolaUnità Operativa Complessa (UOC) Anatomia ed Istologia Patologica e Citologia Diagnostica, Dipartimento dei Servizi Diagnostici e della Farmaceutica, Ospedale Sandro Pertini, Roma, Italy.
Andrea RemoPathology Unit, "Mater Salutis" Hospital, Legnago, Italy.
Mario Rosario D'AndreaUnità Operativa Semplice a valenza Dipartimentale (UOSD) Oncologia, Ospedale S. Paolo, Civitavecchia, Italy.
Giulia CoppolaDepartment of Radiological, Oncological and Pathological Sciences, Sapienza University of Rome, Rome, Italy.
Michele SimboloSection of Pathology, Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.
Erminia ManfrinSection of Pathology, Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.
Aldo ScarpaSection of Pathology, Department of Diagnostics and Public Health, University and Hospital Trust of Verona, Verona, Italy.
Elena De SantisDepartment of Anatomical, Histological, Forensic Medicine and Orthopedic Sciences, Sapienza University of Rome, Rome, Italy.
Guido GiordanoUnit of Medical Oncology and Biomolecular Therapy, Polilinico Riuniti, Foggia, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Sapienza University of Rome · ITOspedale Sandro Pertini · ITOspedale San Paolo · ITUniversity of Foggia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant Brenner Tumor (mBT) is extremely rare. Although BT are almost exclusive ovarian neoplasms, they may constitute a highly unusual tumor of the testis; in fact, only seven fully documented cases have been reported to date. Because of their rarity, the pathogenesis of these tumors has not been clarified and there is no standard therapeutic approach. We report the first case of epididymal mBT with synchronous, multiple, liver metastases and a very dramatic clinical course. Both primary tumor and metastasis were subjected to mutational analysis of 20 cancer associated genes. Primary tumor showed

Indexed as

Brenner tumorcase reportepididymisFGFRliver metastasesmalignantmutationstestis

Identifiers

PMID33912469
PMCPMC8072450
OpenAlexW3156290346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.