Evidence map›Paper›PMID 33912377›Full record

ArticleNanotechnology reviews2020

Therapeutic strategies and potential implications of silver nanoparticles in the management of skin cancer.

Shaloam Dasari, Clement G Yedjou, Robert T Brodell, Allison R Cruse, Paul B Tchounwou

Open access · goldAbstract read
In one paragraph

Article in Nanotechnology reviews, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Shaloam DasariDepartment of Biology, Environmental Toxicology Research Laboratory, NIH-RCMI Center for Environmental Health, Jackson State University, Jackson, MS 39217, United States of America.
Clement G YedjouDepartment of Biological Sciences, College of Science and Technology, Florida Agricultural and Mechanical University, 1610 S. Martin Luther King Blvd, Tallahassee, FL 32307, United States of America.
Robert T BrodellDepartment of Dermatology, University of Mississippi Medical Center, 2500N. State Street, Jackson, MS 39216, United States of America.
Allison R CruseDepartment of Dermatology, University of Mississippi Medical Center, 2500N. State Street, Jackson, MS 39216, United States of America.
Paul B TchounwouDepartment of Biology, Environmental Toxicology Research Laboratory, NIH-RCMI Center for Environmental Health, Jackson State University, Jackson, MS 39217, United States of America.
Jackson State University · USState Street (United States) · USFlorida Agricultural and Mechanical University · US

Funding

Strengthening the Biomedical Data Science Training Program at Jackson State UniversityU54MD015929 · NIMHD · JACKSON STATE UNIVERSITY · PI NOUBISSI, FELICITE K · 2020 to 2024
$12.1M
RCMI-Center for Environmental HealthG12MD007581 · NIMHD · JACKSON STATE UNIVERSITY · PI TCHOUNWOU, PAUL B. · 2012 to 2017
$11.2M
NIMHD NIH HHS G12 MD007581NIMHD NIH HHS U54 MD015929
6 · The paper itself

Abstract

Skin cancer (SC) is the most common carcinoma affecting 3 million people annually in the United States and millions of people worldwide. It is classified as melanoma SC (MSC) and non-melanoma SC (NMSC). NMSC represents approximately 80% of SC and includes squamous cell carcinoma and basal cell carcinoma. MSC, however, has a higher mortality rate than SC because of its ability to metastasize. SC is a major health problem in the United States with significant morbidity and mortality in the Caucasian population. Treatment options for SC include cryotherapy, excisional surgery, Mohs surgery, curettage and electrodessication, radiation therapy, photodynamic therapy, immunotherapy, and chemotherapy. Treatment is chosen based on the type of SC and the potential for side effects. Novel targeted therapies are being used with increased frequency for large tumors and for metastatic disease. A scoping literature search on PubMed, Google Scholar, and Cancer Registry websites revealed that traditional chemotherapeutic drugs have little effect against SC after the cancer has metastasized. Following an overview of SC biology, epidemiology, and treatment options, this review focuses on the mechanisms of advanced technologies that use silver nanoparticles in SC treatment regimens.

Indexed as

basal cell carcinomabiologyclinical manifestationsepidemiologymalignant melanomasilver nanoparticlesskin cancersquamous cell carcinomatreatment

Identifiers

PMID33912377
PMCPMC8078871
OpenAlexW3125063427

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.