Evidence map›Paper›PMID 33912372›Full record

ArticlePlastic and reconstructive surgery. Global open2021

Survey Outcomes of Lipedema Reduction Surgery in the United States.

Karen L Herbst, Emily A Hansen, Leopoldo M Cobos Salinas, Thomas F Wright, Ethan E Larson, Jaime S Schwartz

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Plastic and reconstructive surgery. Global open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06549738 (Effects of Intermittent Pneumatic Compression Therapy on Tissue Volume, Pain, and Quality of Life in Women Living With Lipedema), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06549738 nacompletednot on this mapstarted 2023, after this paper: background citation

Effects of Intermittent Pneumatic Compression Therapy on Tissue Volume, Pain, and Quality of Life in Women Living With Lipedema

TypeinterventionalSponsorLympha PressRan2023 to 2023Enrolled46ConditionsLipedemaArmsIntermittent pneumatic compression therapy
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 58 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Hybrid approach of massive lipolymphedema of the thigh: A novel surgical technique.Journal of vascular surgery. Venous and lymphatic disorders · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Liposuction as a Treatment for Lipedema: A Scoping Review.Plastic and reconstructive surgery. Global open · 2024
    Article
  13. Article
  14. Review
  15. Observational
  16. Article
  17. Article
  18. The Advanced Care Study: Current Status of Lipedema in Spain, A Descriptive Cross-Sectional Study.International journal of environmental research and public health · 2023
    Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Karen L HerbstDepartment of Medicine, University of Arizona, Tucson, Ariz.
Emily A HansenTREAT Program, University of Arizona, Tucson, Ariz.
Leopoldo M Cobos SalinasTREAT Program, University of Arizona, Tucson, Ariz.
Thomas F WrightLipedema Surgical Solutions, St. Louis, Mo.
Ethan E LarsonLarson Plastic Surgery, Tucson, Ariz.
Jaime S SchwartzTotal Lipedema Care, Los Angeles, Calif.
University of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLipedema is a loose connective tissue disease affecting the limbs of women, that is difficult to lose by diet, exercise, or bariatric surgery. Publications from Europe demonstrate that lipedema reduction surgery improves quality of life for women with lipedema. There are no comparable studies in the United States (USA). The aim of this study was to collect data from women with lipedema in the USA who have undergone lipedema reduction surgery in the USA to determine if quality of life, pain, and other measures improved after lipedema reduction surgery.

methodsSubjects were recruited and consented online for a 166-item questionnaire in REDCap. In total, 148 women answered the questionnaire after undergoing lipedema reduction surgery in the USA. Significance set at

resultsQuality of life improved in 84% and pain improved in 86% of patients. Ambulation improved most in lipedema Stage 3 (96%). Weight loss occurred in all stages by 3 months after surgery. Complications included growth of loose connective tissue within and outside treated areas, tissue fibrosis, anemia, blood clots, and lymphedema.

conclusionsWomen with lipedema noticed significant benefits after lipedema reduction surgery in the USA. Prospective studies are needed to assess benefits and complications after lipedema reduction surgery in the USA.

Identifiers

PMID33912372
PMCPMC8078351
OpenAlexW3158536041

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.