ArticleEcancermedicalscience2021
Factors associated with advanced-stage diagnosis of breast cancer in north-west Ethiopia: a cross-sectional study.
Article in Ecancermedicalscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 7 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 7 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Stage at Diagnosis and Molecular Subtype Distribution of Breast Cancer in Sub-Saharan Africa: A Systematic Review.Cancer reports (Hoboken, N.J.) · 2026Pooled it
- The Impact of Travel Distance on Cancer Stage at Diagnosis for Cancer: A Systematic Review.International journal of environmental research and public health · 2025Pooled it
- Epidemiology and clinical characteristics of breast cancer in Ethiopia: a systematic review.BMC cancer · 2024Pooled it
- Proportion of early-stage breast cancer at diagnosis in Ethiopia: a systematic review and meta-analysis.BMC cancer · 2024Pooled it
- Advanced-stage breast cancer diagnosis and its determinants in Ethiopia: a systematic review and meta-analysis.BMC women's health · 2024Pooled it
- Late-stage diagnosis: The driving force behind high breast cancer mortality in Ethiopia: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Benefits of breast self-examinations for medically underserved populations: A systematic review.Women's health (London, England)Pooled it
- Transportation-related factors, cancer screening, and stage at diagnosis: A scoping review.PloS one · 2026Article
- Spatial Distribution of Breast Cancer in Morocco and the Impact of Travel Distance and Rural Residence on Cancer Stage.Epidemiologia (Basel, Switzerland) · 2025Article
- Travel burden increases the risk of advanced stage at diagnosis of breast cancer in Kashgar, China.Scientific reports · 2025Article
- Predictors of advanced-stage presentation among patients with a diagnosis of breast and cervical cancer in Ethiopia.The oncologist · 2025Article
- Article
- Willingness and ability to pay for breast cancer treatment among patients from Addis Ababa, Ethiopia: A cross-sectional study.PloS one · 2024Article
- The practice of breast self-examination and associated factors among female healthcare professionals working in selected hospitals in Kigali, Rwanda: a cross sectional study.BMC women's health · 2023Article
- Risk factors for breast cancer among women in Ekurhuleni Metropolitan Municipality, Gauteng province of South Africa, 2017‒2020: a case-control study.Ecancermedicalscience · 2023Article
- Determinants of breast cancer in Ethiopia: a systematic review and meta-analysis.Ecancermedicalscience · 2023Review
- Modifiable Factors Associated With Delayed Diagnosis of Breast Cancer in Pakistan: An Epidemiological Study.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBreast cancer tumours are the most common malignant tumours among women in Ethiopia. Although advanced-stage diagnosis of breast cancer is a common problem, evidence-based information is lacking about the magnitude and determinants of advanced-stage presentation in north-west Ethiopia.
methodsAn institution-based, cross-sectional study was conducted at the oncology units of the University of Gondar and Felege Hiwot specialised hospitals. Stages III and IV were considered advanced stage, whereas stages I and II were considered early stages. Data were collected prospectively on newly diagnosed breast cancer patients and entered using the EPI Info version 7.2 and analysed using Statistical Package for the Social Sciences version 23. Multivariable logistic regression was used to identify the determinants of advanced-stage diagnosis of breast cancer. A
resultAbout 71.2% of breast cancer patients presented with advanced-stage disease. The median age of patients was 40 years. Rural residence (adjusted odds ratio (AOR) = 1.7; 95% confidence interval (CI): 1.02, 2.96), painless breast lump/wound (AOR = 2.5; 95% CI: 1.45, 4.13), travel distance ≥5 km (AOR = 3.2; 95% CI: 1.72, 5.29), not practising breast self-examination (BSE) (AOR = 2.9; 95% CI: 1.30, 6.52), time to presentation ≥3 months (AOR = 1.4; 95% CI: 1.02, 2.37) and misdiagnosed at first visit (AOR = 1.9; 95% CI: 1.09, 3.59) were determinants of advanced-stage breast cancer.
conclusionNearly three-quarters of the patients were diagnosed with advanced-stage breast cancer. Not practising BSE, travel distance ≥5 km, rural residence, painless breast wound/lump and being misdiagnosed at first visit were important determinants of advanced-stage diagnosis of breast cancer. Focused awareness creation programmes for the public and increasing cancer diagnostic centres in the country are crucial to downstage breast cancer at presentation.
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