Evidence map›Paper›PMID 33912182›Full record

ArticleFrontiers in immunology2021

A Novel Image Analysis Approach Reveals a Role for Complement Receptors 1 and 2 in Follicular Dendritic Cell Organization in Germinal Centers.

Jessica C Anania, Annika Westin, Jeremy Adler, Birgitta Heyman

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Complement Inhibition in Kidney Transplantation: Where Are We Now?BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2023
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jessica C AnaniaDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Annika WestinDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Jeremy AdlerDepartment of Immunology, Genetics and Pathology, Facilities, BioVis, Uppsala University, Uppsala, Sweden.
Birgitta HeymanDepartment of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.
Uppsala University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Follicular dendritic cells (FDCs) are rare and enigmatic cells that mainly reside in germinal centers (GCs). They are capable of capturing immune complexes,

Indexed as

Molecular ImagingAnimalsAntibody FormationAntigen-Antibody ComplexBiomarkersB-LymphocytesDendritic Cells, FollicularFemaleFluorescent Antibody TechniqueGerminal CenterImmunophenotypingMaleMiceMice, KnockoutReceptors, ComplementReceptors, Complement 3dAntigen-Antibody ComplexBiomarkersimmunoglobulin M receptorReceptors, ComplementReceptors, Complement 3dReceptors, Fccomplement receptorFc receptorfollicular dendritic cell (FDC)germinal center (GC)IgM receptorImageJ macroimmune complex (IC)

Identifiers

PMID33912182
PMCPMC8072117
OpenAlexW3155205859

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.