Evidence map›Paper›PMID 33912159›Full record

ArticleFrontiers in immunology2021

The

Gema Perez-Chacon, Juan M Zapata

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Gema Perez-ChaconInstituto de Investigaciones Biomédicas "Alberto Sols", CSIC-UAM, Madrid, Spain.
Juan M ZapataInstituto de Investigaciones Biomédicas "Alberto Sols", CSIC-UAM, Madrid, Spain.
Instituto de Investigaciones Biomédicas Sols-Morreale · ESUniversidad Autónoma de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic lymphocytic leukemia (CLL)/Small lymphocytic lymphoma (SLL) is a heterogeneous disease consisting of at least two separate subtypes, based on the mutation status of the immunoglobulin heavy chain variable gene (IGHV) sequence. Exposure to antigens seems to play a role in malignant transformation and in the selection and expansion of more aggressive CLL clones. Furthermore, a biased usage of particular IGHV gene subgroups and the existence of stereotyped B-cell receptors (BCRs) are distinctive characteristics of human CLL. We have previously described that

Indexed as

Genes, Immunoglobulin Heavy ChainAnimalsComplementarity Determining RegionsDisease Models, AnimalFemaleHumansImmunoglobulin Variable RegionInfantLeukemia, Lymphocytic, Chronic, B-CellMaleMiceMice, Inbred BALB CMutationProto-Oncogene Proteins c-bcl-2Receptors, Antigen, B-CellSomatic Hypermutation, ImmunoglobulinComplementarity Determining RegionsImmunoglobulin Variable RegionProto-Oncogene Proteins c-bcl-2Receptors, Antigen, B-CellTNF Receptor-Associated Factor 2TRAF2 protein, mouseBCL2BCR stereotipychronic lymphocytic leukemiaCLLIGHVsmall lymphocytic lymphomaTRAF2

Identifiers

PMID33912159
PMCPMC8072112
OpenAlexW3152757197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.