Evidence map›Paper›PMID 33912056›Full record

ArticleFrontiers in pharmacology2021

P- Hydroxybenzyl Alcohol Alleviates Oxidative Stress in a Nonalcoholic Fatty Liver Disease Larval Zebrafish Model and a BRL-3A Hepatocyte

Jing An, Lijun Cheng, Liping Yang, Nali Song, Ju Zhang, Kejian Ma, Ji Ma

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Oxidative medicine and cellular longevity · 2022
    Article
  9. Zebrafish and Flavonoids: Adjuvants against Obesity.Molecules (Basel, Switzerland) · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Jing AnCentral Laboratory, Yunnan Institute of Traditional Chinese Medicine and Materia Medica, Kunming, China.
Lijun ChengZhao Tong University, Zhaotong, China.
Liping YangYunnan Key Laboratory for Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming, China.
Nali SongCentral Laboratory, Yunnan Institute of Traditional Chinese Medicine and Materia Medica, Kunming, China.
Ju ZhangCentral Laboratory, Yunnan Institute of Traditional Chinese Medicine and Materia Medica, Kunming, China.
Kejian MaCentral Laboratory, Yunnan Institute of Traditional Chinese Medicine and Materia Medica, Kunming, China.
Ji MaCentral Laboratory, Yunnan Institute of Traditional Chinese Medicine and Materia Medica, Kunming, China.
Yunnan University of Traditional Chinese Medicine · CNChina Pharmaceutical University · CNYunnan University · CNZhaotong University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease, and it has gradually become the main disease burden in the world. However, the pathogenesis of NAFLD is complex, involving such things as dyslipidemia, oxidative stress, inflammation, etc. This brings to the table a significant challenge for drug development, and there is still no drug approved by the FDA on the market to treat the disease. GAS and HBA are active ingredients of the

Indexed as

non-alcoholic fatty liver diseaseNrf2-HO-1 pathwayoxidative stressP-hydroxybenzyl alcoholzebrafish

Identifiers

PMID33912056
PMCPMC8071996
OpenAlexW3155524162

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.