ArticleFrontiers in neuroscience2021
Baseline Cerebral Ischemic Core Quantified by Different Automatic Software and Its Predictive Value for Clinical Outcome.
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed, 27 citations in OpenAlex.
- Article
- Adjunctive Human Urinary Kallidinogenase Enhances the Cognitive and Hemodynamic Outcomes of Anterior Circulation Stenting.Translational stroke research · 2025Article
- Favorable Cerebral Collateral Cascades Improve Futile Recanalization by Reducing Ischemic Core Volume in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment.Translational stroke research · 2025Article
- High ischemic deficit in computed tomography perfusion is a risk factor for cerebral vascular ischemic events in Takayasu arteritis: a prospective observational study.BMC rheumatology · 2025Article
- Predictive value of the combined use of computed tomography perfusion imaging and blood pressure levels for the prognosis of patients with acute ischemic stroke.The Journal of international medical research · 2025Article
- Infarct Growth Rate Predicts Early Neurological Improvement in Ischemic Stroke After Endovascular Thrombectomy.Brain sciences · 2025Article
- Assessment of Perfusion Volumes by a New Automated Software for Computed Tomography Perfusion.Stroke and vascular neurology · 2024Article
- Left atrial myxoma as a rare cause of stroke.Heliyon · 2024Article
- Lean body mass and stroke volume, a sex issue.Frontiers in neurology · 2024Article
- Perfusion deficits in thrombolysis-treated acute ischemic stroke patients with negative or positive diffusion-weighted imaging.BMC neurology · 2023Observational
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- Stroke recurrence is associated with unfavorable intracranial venous outflow in patients with symptomatic intracranial atherosclerotic large vessel severe stenosis or occlusion.Frontiers in neurology · 2023Article
- The diagnostic value of quantitative parameters on dual-layer detector-based spectral CT in identifying ischaemic stroke.Frontiers in neurology · 2023Article
- Agreement between estimated computed tomography perfusion ischemic core and follow-up infarct on diffusion-weighted imaging.Insights into imaging · 2022Article
- Multicentre registration of wake-up stroke in China (MCRWUSC): a protocol for a prospective, multicentre, registry-based cohort study.BMJ open · 2022Article
- Cerebral Venous Oxygen Saturation in Hypoperfusion Regions May Become a New Imaging Indicator to Predict the Clinical Outcome of Stroke.Life (Basel, Switzerland) · 2022Article
- Quantitative Distribution of Cerebral Venous Oxygen Saturation and Its Prognostic Value in Patients with Acute Ischemic Stroke.Brain sciences · 2022Article
- Article
- Clinical Imaging of the Penumbra in Ischemic Stroke: From the Concept to the Era of Mechanical Thrombectomy.Frontiers in cardiovascular medicine · 2022Review
- Deep learning-based identification of acute ischemic core and deficit from non-contrast CT and CTA.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021Article
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Authors and funding
10 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aims to investigate the agreement of three software packages in measuring baseline ischemic core volume (ICV) and penumbra volume (PV), and determine their predictive values for unfavorable clinical outcome in patients with endovascular thrombectomy (EVT).
methodsPatients with acute ischemic stroke who underwent computed tomographic perfusion (CTP) were recruited. Baseline CTP measurements including ICV and PV were calculated by three software packages of IntelliSpace Portal (ISP), Rapid Processing of Perfusion and Diffusion (RAPID), and fast-processing of ischemic stroke (F-STROKE). All patients received EVT, and the modified Rankin scale (mRS) at 90 days after EVT was assessed to determine the clinical outcomes (favorable: mRS = 0-2; unfavorable: mRS = 3-6). The agreement of CTP measurements among three software packages was determined using intraclass correlation coefficient (ICC). The associations between CTP measurements and unfavorable clinical outcome were analyzed using logistic regression. Receiver operating characteristic curves were conducted to calculate the area under the curve (AUC) of CTP measurements in predicting unfavorable clinical outcome.
resultsOf 223 recruited patients (68.2 ± 11.3 years old; 145 males), 17.0% had unfavorable clinical outcome after EVT. Excellent agreement between F-STROKE and RAPID was found in measuring ICV (ICC 0.965; 95% CI 0.956-0.973) and PV (ICC 0.966; 95% CI 0.956-0.973). ICVs measured by three software packages were significantly associated with unfavorable clinical outcome before (odds ratios 1.012-1.018, all
conclusionsThe software of F-STROKE has excellent agreement with the widely used analysis tool of RAPID in measuring ICV and PV. The ischemic core volume measured by both F-STROKE and RAPID is a stronger predictor for unfavorable clinical outcome after EVT compared to ISP.
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