Evidence map›Paper›PMID 33911867›Full record

ArticleNeuropsychiatric disease and treatment2021

Clinical Characteristics and Management of Cerebral Venous Sinus Thrombosis in Patients with Essential Thrombocythemia.

Lidong Jiao, Xiaoqin Huang, Chunqiu Fan, Hong Zhao, Zhen Li, Huixin Shen, Jian Chen, Jiangang Duan

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Lidong JiaoDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0003-2728-5344
Xiaoqin HuangDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0001-6148-3577
Chunqiu FanDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Hong ZhaoDepartment of Hematology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Zhen LiDepartment of Ophthalmology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Huixin ShenDepartment of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.ORCID 0000-0001-8276-7608
Jian ChenDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Jiangang DuanDepartment of Emergency, Xuanwu Hospital, Capital Medical University, Beijing, People's Republic of China.
Capital Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveEssential thrombocythemia (ET) is a rare cause of cerebral venous sinus thrombosis (CVST). Analysis of the risk factors and treatment therapies of CVST in ET has yielded controversial findings. SUBJECTS AND

methodsWe retrospectively investigated the clinical characteristics of CVST events in ET and compared baseline characteristics, causative factors, hematological effects, and treatments between ET patients with and without CVST.

resultsOverall, 91 of 115 patients who met the ET diagnosis were included in this study. Among them, 23 (25.27%) patients met the diagnostic criteria of ET with CVST for inclusion, 14 (60.87%) of whom were females, with a median age of 34 (range 25-50). CVST diagnosis was made concomitantly to ET in 19 patients (82.61%). The most common symptom and sites of thrombosis of CVST was an acute or subacute headache and sigmoid sinuses, respectively. Compared with ET patients without CVST, ET patients with CVST were significantly younger (37.65±14.45 vs 60.93±13.46,

conclusionMost patients (95.65%) had a favorable outcome without recurrence after standard anticoagulant and cytoreductive treatment at last follow-up. These findings indicate that CVST may be the initial presentation of ET, with its detection crucial for early diagnosis and appropriate management. Anticoagulant and cytoreductive therapies should be recommended for preventing ET-related CVST with

Indexed as

anticoagulant therapycerebral venous thrombosiscytoreductive therapyessential thrombocythemiaJAK2 V617F

Identifiers

PMID33911867
PMCPMC8075307
OpenAlexW3152908197

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.