ReviewNeuropsychiatric disease and treatment2021
Exploring the Hereditary Nature of Migraine.
Review in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- A Comprehensive Investigation into the Association Between Mthfr C677t, A1298c, and Ace I/D Variants and Risk of Migraine: an Updated Meta-Analysis of Genetic Association Studies with Trial Sequential Analysis and Meta-Regression.Journal of molecular neuroscience : MN · 2023Pooled it
- Deciphering the Role of the rs2651899, rs10166942, and rs11172113 Polymorphisms in Migraine: A Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Review
- Pediatric migraine: Neurodevelopmental mechanisms, clinical phenotypes, and modern therapeutics.World journal of clinical pediatrics · 2026Review
- Maternal and child mental health and incident migraine in adolescence: An "All Our Families" prospective cohort study.Headache · 2026Article
- Pharmacological mechanisms underlying neurovascular alterations related to resistant and refractory migraine: CGRP pathways and beyond.The journal of headache and pain · 2026Review
- Epigenetics in migraine: the Junior Editorial Board Members' vision.The journal of headache and pain · 2025Review
- Integrated ATAC-seq and RNA-seq analysis identifies Grid2 and Reln as potential regulatory genes in migraine pathophysiology.The journal of headache and pain · 2025Article
- Assessing Self-medication Practices Among Healthcare Providers With Migraine in Saudi Arabia.Brain and behavior · 2025Article
- Clinical evaluation of zavegepant for the acute treatment of migraine.Journal of managed care & specialty pharmacy · 2025Review
- Prognostic Value of Minnesota Multiphasic Personality Inventory-2 (MMPI-2) Profiles in Predicting Outcomes of Occipital Nerve Stimulation for Refractory Chronic Migraine: A Retrospective Bias-Corrected Multivariable Analysis.Current pain and headache reports · 2025Review
- Up-regulation of MAPK14-related lncRNAs in the circulation of migraineurs.Scientific reports · 2025Article
- Decoding migraine disorders: parathyroid hormone-related peptide receptors as key genetic drivers.Brain communications · 2025Article
- Migraine Headache and Its Related Disability Factors Among University Students in Jordan: A Cross-Sectional Study.Journal of pain research · 2025Article
- Causal Effects of Sleep Quality on Primary Headache and the Mediation via Gut Microbiota: A Mendelian Randomization Study.Brain and behavior · 2024Article
- An Integrative Migraine Polygenic Risk Score Is Associated with Age at Onset But Not Chronification.Journal of clinical medicine · 2024Article
- Multimodal Migraine Management and the Pursuit of Migraine Freedom: A Narrative Review.Neurology and therapy · 2023Review
- Non-coding variants in VAMP2 and SNAP25 affect gene expression: potential implications in migraine susceptibility.The journal of headache and pain · 2023Article
- Galcanezumab effects on incidence of headache after occurrence of triggers, premonitory symptoms, and aura in responders, non-responders, super-responders, and super non-responders.The journal of headache and pain · 2023Observational
- Genetics of migraine: where are we now?The journal of headache and pain · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Migraine is a common neurological disorder which affects 15-20% of the population; it has a high socioeconomic impact through treatment and loss of productivity. Current forms of diagnosis are primarily clinical and can be difficult owing to comorbidity and symptom overlap with other neurological disorders. As such, there is a need for better diagnostic tools in the form of genetic testing. Migraine is a complex disorder, encompassing various subtypes, and has a large genetic component. Genetic studies conducted on rare monogenic subtypes, including familial hemiplegic migraine, have led to insights into its pathogenesis via identification of causal mutations in three genes (
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.