ArticleAnnals of dermatology2020
Late Onset Foreign Body Reaction due to Poly-L-Lactic Acid Facial Injections for Cosmetic Purpose.
Article in Annals of dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Long-Term In Vivo Biological Performance of PLLA-b-PEG/HA Filler.Journal of functional biomaterials · 2026Article
- The Management of Poly-L-Lactic Acid (PLLA) Nodules: A Scoping Review and Evidence-Mapped Clinical Pathway.Cureus · 2026Review
- Non-ablative dermis layer targeted dielectric heating for facial rhytid improvement in Asian skin.JPRAS open · 2026Article
- Reactive Palatal Fibrosis Following Facial Dermal Filler Injection and Anfiye Inhalation: A Case Mimicking OSMF.Clinical case reports · 2026Article
- Preparation of Uniform PEG-PLLA Microspheres via Membrane Emulsification for Soft Tissue Filling Applications.Journal of functional biomaterials · 2026Article
- Facial Injectable Fillers in Aesthetic Medicine: Clinical Applications and Safety Strategies.Medical science monitor : international medical journal of experimental and clinical research · 2025Review
- Transepidermal Delivery of Calcium Hydroxyapatite (CaHA) Microneedling: A Novel Approach for Inducing Collagen Types III and IV.Biomedicines · 2025Article
- Article
- Comparative Analysis of Reconstitution and Solubility of Two Poly-L-Lactic Acid Fillers for Medical Applications.Polymers · 2025Article
- Alopecia secondary to poly-L-lactic acid dermal fillers.JAAD case reports · 2025Article
- Enhancing Facial Projection: Efficacy and Safety of a Novel Filler Combining Cross-Linked Sodium Hyaluronate Gel With Poly-L-Lactic Acid-b-PEG Microspheres for T-Zone Augmentation.Journal of cosmetic dermatology · 2025Article
- The Redefinition and Volumization of the Lip Area with Hyaluronic Acid: A Case Series.Journal of clinical medicine · 2024Article
- Comparison of Different Types of Poly-L-Lactic Acid Microspheres In Vitro and In Vivo Studies.Aesthetic surgery journal. Open forum · 2024Article
- Recent progress and clinical applications of advanced biomaterials in cosmetic surgery.Regenerative biomaterials · 2023Review
- Biocompatibility and degradation comparisons of four biodegradable copolymeric osteosynthesis systems used in maxillofacial surgery: A goat model with four years follow-up.Bioactive materials · 2022Article
- Biocompatibility Study of Electrospun Nanocomposite Membranes Based on Chitosan/Polyvinyl Alcohol/Oxidized Carbon Nano-Onions.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The safety and efficacy of Poly-L-lactic acid (PLLA) as an injectable facial volumizer for the treatment of lipoatrophy and facial rejuvenation has been widely proven. We experienced a remarkable case of deep-seated nodules on both the cheeks of 57-year-old female 18-months after administration of PLLA filler injection for cosmetic purpose and performed a skin biopsy. With hematoxylin and eosin stain, the nodule showed non-caseating granulomas consisting of histiocytes with central foreign bodies in the dermis. This case report represents the late-onset foreign body reaction due to PLLA facial injections.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.