Evidence map›Paper›PMID 33911790›Full record

ArticleAnnals of dermatology2020

pH-Dependent Expression, Stability, and Activity of

Minji Park, Ji Su Lee, Won Hee Jung, Yang Won Lee

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Annals of dermatology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07433907 (A Prospective, Randomized, Split-Face Pilot Study Comparing the Efficacy of the Institute of Dermatology's Antioxidant Moisturizing Serum in Mild to Moderate Seborrheic Dermatitis), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07433907 nacompletednot on this mapstarted 2026, after this paper: background citation

A Prospective, Randomized, Split-Face Pilot Study Comparing the Efficacy of the Institute of Dermatology's Antioxidant Moisturizing Serum in Mild to Moderate Seborrheic Dermatitis

TypeinterventionalSponsorInstitute of Dermatology, ThailandRan2026 to 2026Enrolled13ConditionsSeborrheic Dermatitis on the FaceArmsAntioxidant moisturizing serum
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Head and neck dermatitis is exacerbated byFrontiers in immunology · 2023
    Article
  4. Skin Commensal FungusJournal of microbiology and biotechnology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Minji ParkDepartment of Systems Biotechnology, Chung-Ang University, Anseong, Korea.ORCID https://orcid.org/0000-0002-2738-9517
Ji Su LeeDepartment of Dermatology, Konkuk University School of Medicine, Korea.ORCID https://orcid.org/0000-0002-7270-2875
Won Hee JungDepartment of Systems Biotechnology, Chung-Ang University, Anseong, Korea.ORCID https://orcid.org/0000-0002-6920-0233
Yang Won LeeDepartment of Dermatology, Konkuk University School of Medicine, Korea.ORCID https://orcid.org/0000-0003-1268-1248
Chung-Ang University · KRKonkuk University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe lipophilic yeasts

objectiveIn this study, we aimed to analyze the activity, stability, and expression of MrLip5, with particular focus on pH.

methodsWe heterologously expressed MrLip5 in

resultsWe found that MrLip5 was most active and stable and highly expressed under alkaline conditions, which is similar to that of the diseased skin surface.

conclusionOur results suggest that the activity and expression of MrLip5 are pH-dependent, and that this lipase may play an essential role at the

Indexed as

LipaseMalassezia restrictaMrLip5pH

Identifiers

PMID33911790
PMCPMC7875232
OpenAlexW3101646413

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.