Evidence map›Paper›PMID 33911286›Full record

ArticleNature2021

Expanded diversity of Asgard archaea and their relationships with eukaryotes.

Yang Liu, Kira S Makarova, Wen-Cong Huang, Yuri I Wolf, Anastasia N Nikolskaya, Xinxu Zhang, Mingwei Cai, Cui-Jing Zhang, Wei Xu, Zhuhua Luo and 3 more

Open access · greenAbstract read
In one paragraph

Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed
22.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 329 citations in OpenAlex.

  1. Article
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  7. Divergent evolution of the PRPS enzymes across the tree of life.bioRxiv : the preprint server for biology · 2026
    Article
  8. Review
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  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. The archaeal roots of eukaryotic life.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  18. Article
  19. Toward a genomic understanding of the tree of life.Molecular biology and evolution · 2026
    Article
  20. Review

120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 3 countries.

Yang Liu *Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, P. R. China.ORCID http://orcid.org/0000-0002-1109-0756
Kira S Makarova *National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-8174-2844
Wen-Cong Huang *Shenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, P. R. China.ORCID http://orcid.org/0000-0002-1328-4087
Yuri I WolfNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.ORCID http://orcid.org/0000-0002-0247-8708
Anastasia N NikolskayaNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA.
Xinxu ZhangShenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, P. R. China.ORCID http://orcid.org/0000-0002-4299-2795
Mingwei CaiShenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, P. R. China.ORCID http://orcid.org/0000-0002-2757-6742
Cui-Jing ZhangShenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, P. R. China.ORCID http://orcid.org/0000-0003-0904-5531
Wei XuKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen, P. R. China.ORCID http://orcid.org/0000-0003-0213-8823
Zhuhua LuoKey Laboratory of Marine Biogenetic Resources, Third Institute of Oceanography, Ministry of Natural Resources, Xiamen, P. R. China.ORCID http://orcid.org/0000-0002-7553-8628
Lei ChengKey Laboratory of Development and Application of Rural Renewable Energy, Biogas Institute of Ministry of Agriculture, Chengdu, P. R. China.ORCID http://orcid.org/0000-0003-1178-8190
Eugene V KooninNational Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA. koonin@ncbi.nlm.nih.gov.ORCID http://orcid.org/0000-0003-3943-8299
Meng LiShenzhen Key Laboratory of Marine Microbiome Engineering, Institute for Advanced Study, Shenzhen University, Shenzhen, P. R. China. limeng848@szu.edu.cn.ORCID http://orcid.org/0000-0001-8675-0758
Shenzhen University · CNNational Institutes of Health · USMinistry of Natural Resources · CNBiogas Institute of Ministry of Agriculture · CN

Funding

Comparative Analysis Of Completely Sequenced GenomesZIALM000073 · NLM · NATIONAL LIBRARY OF MEDICINE · PI KOONIN, EUGENE V · 2009 to 2025
$43.1M
Finding Protein Sequence Motifs--Methods And ApplicationsZIALM000061 · NLM · NATIONAL LIBRARY OF MEDICINE · PI KOONIN, EUGENE V · 2009 to 2025
$10.6M
Intramural NIH HHS ZIA LM000073
6 · The paper itself

Abstract

Asgard is a recently discovered superphylum of archaea that appears to include the closest archaeal relatives of eukaryotes

Indexed as

Genome, ArchaealPhylogenyArchaeaBiological EvolutionEukaryotaMetagenomics

Identifiers

PMID33911286
PMCPMC11165668
OpenAlexW3158701946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.