Evidence map›Paper›PMID 33911184›Full record

ArticleScientific reports2021

The risk of developing a meningioma during and after pregnancy.

Jenny Pettersson-Segerlind, Tiit Mathiesen, Adrian Elmi-Terander, Erik Edström, Mats Talbäck, Maria Feychting, Giorgio Tettamanti

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 28 citations in OpenAlex.

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  7. Malignant Meningiomas: From Diagnostics to Treatment.Diagnostics (Basel, Switzerland) · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jenny Pettersson-SegerlindDepartment of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden.
Tiit MathiesenDepartment of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
Adrian Elmi-TeranderDepartment of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden.
Erik EdströmDepartment of Neurosurgery, Karolinska University Hospital, Stockholm, Sweden.
Mats TalbäckUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Maria FeychtingUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Giorgio TettamantiUnit of Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden. giorgio.tettamanti@ki.se.
Karolinska Institutet · SEKarolinska University Hospital · SERigshospitalet · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pregnancy has been associated with diagnosis or growth of meningiomas in several case reports, which has led to the hypothesis that pregnancy may be a risk factor for meningiomas. The aim of this study was to test this hypothesis in a large population-based cohort study. Women born in Sweden 1958-2000 (N = 2,204,126) were identified and matched with the Medical Birth Register and the Cancer Register. The expected number of meningioma cases and risk ratios were calculated for parous and nulliparous women and compared to the observed number of cases. Compared to parous women, meningiomas were more common among nulliparous (SIR = 1.73; 95% CI 1.52-1.95). The number of meningioma cases detected during pregnancy was lower than the expected (SIR = 0.40; 95% CI 0.20-0.72). Moreover, no increased risk was found in the first-year post-partum (SIR = 1.04; 95% CI 0.74-1.41). Contrary to our hypothesis, there was no increased risk for diagnosing a meningioma during pregnancy or 1-year post-partum. A lower detection rate during pregnancy, may reflect under-utilization of diagnostic procedures, but the actual number of meningiomas was homogenously lower among parous than nulliparous women throughout the study period, indicating that pregnancy is not a risk factor for meningioma.

Indexed as

AdolescentAdultCohort StudiesFemaleHumansIncidenceMeningeal NeoplasmsMeningiomaMiddle AgedParityPregnancyPregnancy Complications, NeoplasticRisk FactorsSwedenYoung Adult

Identifiers

PMID33911184
PMCPMC8080659
OpenAlexW3158337949

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.