Evidence map›Paper›PMID 33911182›Full record

ArticleScientific reports2021

Nanaomycin K inhibited epithelial mesenchymal transition and tumor growth in bladder cancer cells in vitro and in vivo.

Koichi Kitagawa, Katsumi Shigemura, Aya Ishii, Takuji Nakashima, Hirotaka Matsuo, Yoko Takahashi, Satoshi Omura, Jun Nakanishi, Masato Fujisawa

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Natural Compounds and Health Benefits ofMolecules (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Koichi Kitagawa *Department of Advanced Medical Science, Kobe University Graduate School of Science, Technology and Innovation, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe, 650-0017, Japan.
Katsumi ShigemuraDepartment of Public Health, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku, Kobe, 654-0142, Japan. katsumi@med.kobe-u.ac.jp.
Aya Ishii *Department of Public Health, Kobe University Graduate School of Health Sciences, 7-10-2 Tomogaoka, Suma-ku, Kobe, 654-0142, Japan.
Takuji NakashimaKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Hirotaka MatsuoKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Yoko TakahashiKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Satoshi OmuraKitasato Institute for Life Sciences, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo, 108-8641, Japan.
Jun NakanishiResearch Center for Functional Materials, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba, Ibaraki, 305-0044, Japan.
Masato FujisawaDepartment of Urology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan.
Kitasato Institute Hospital · JPKobe University · JPNational Institute for Materials Science · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanaomycin K, derived from Streptomyces rosa subsp. notoensis OS-3966

Indexed as

Epithelial-Mesenchymal TransitionAnimalsApoptosisBenzoisochromanequinonesCell MovementCell ProliferationHumansIn Vitro TechniquesMaleMiceMice, Inbred BALB CMice, NudeNaphthoquinonesTumor Cells, CulturedUrinary Bladder NeoplasmsXenograft Model Antitumor AssaysBenzoisochromanequinonesnanaomycin KNaphthoquinones

Identifiers

PMID33911182
PMCPMC8080577
OpenAlexW3158655168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.