Evidence map›Paper›PMID 33911032›Full record

Trial reportPediatrics2021

A Health-Literacy Intervention for Early Childhood Obesity Prevention: A Cluster-Randomized Controlled Trial.

Lee M Sanders, Eliana M Perrin, H Shonna Yin, Alan M Delamater, Kori B Flower, Aihua Bian, Jonathan S Schildcrout, Russell L Rothman, Greenlight Study Team

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
5.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

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  19. Forty Years of Behavioral Diabetes Research: A Personal Journey.Diabetes spectrum : a publication of the American Diabetes Association · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Lee M SandersDivision of General Pediatrics, Department of Pediatrics, Center for Policy, Outcomes and Prevention, Stanford University, Stanford, California; leesanders@stanford.edu.
Eliana M PerrinDivision of Primary Care and Duke Center for Childhood Obesity Research, Department of Pediatrics, Medical Center, Duke University, Durham, North Carolina.
H Shonna YinDepartment of Pediatrics and Population Health, School of Medicine, New York University and Department of Pediatrics, Bellevue Hospital Center, New York City, New York.
Alan M DelamaterDepartment of Pediatrics, School of Medicine, University of Miami, Miami, Florida.
Kori B FlowerDepartment of Biostatistics and.
Aihua BianDivision of General Pediatrics and Adolescent Medicine, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Jonathan S SchildcroutDivision of General Pediatrics and Adolescent Medicine, Department of Pediatrics, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Russell L RothmanCenter for Health Services Research, Vanderbilt University Medical Center, Nashville, Tennessee; and.
Greenlight Study Team
University of North Carolina at Chapel Hill · USDuke University · USNew York University · USStanford University · USUniversity of Miami · USVanderbilt University Medical Center · US

Funding

UNC CLINICAL AND TRANSLATIONAL SCIENCE AWARD: BPCAUL1RR025747 · NCRR · UNIV OF NORTH CAROLINA CHAPEL HILL · PI RUNGE, MARSCHALL S. · 2008 to 2011
$44.6M
The Vanderbilt Institute for Clinical and Translational Research (VICTR)UL1TR000445 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BERNARD, GORDON RAPHAEL · 2012 to 2016
$41.4M
INSTITUTIONAL CLINICAL AND TRANSLATIONAL SCIENCE AWARDUL1RR029893 · NCRR · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL · 2009 to 2011
$17.7M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Role of Parent Health Literacy in Early Child Obesity and Other Health OutcomesR01HD059794 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI DELAMATER, ALAN M, PERRIN, ELIANA M. · 2009 to 2018
$6.7M
Visuospatial Cognitive Deficit in Del22q11.2 SyndromeR01HD042974 · NICHD · UNIVERSITY OF CALIFORNIA DAVIS · PI SIMON, TONY J · 2003 to 2013
$4.9M
Learning How To Keep TABS (Talking about BMI Screening)K23HD051817 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PERRIN, ELIANA M. · 2006 to 2010
$663k
NCATS NIH HHS UL1 TR000445NCRR NIH HHS UL1 RR025747NCRR NIH HHS UL1 RR029893NICHD NIH HHS K23 HD051817NICHD NIH HHS R01 HD042974NICHD NIH HHS R01 HD059794NIDDK NIH HHS P30 DK111022
6 · The paper itself

Abstract

BACKGROUND AND

objectivesChildren who become overweight by age 2 have greater risk of long-term obesity and health problems. The study aim was to assess the effectiveness of a primary care-based intervention on the prevalence of overweight at age 24 months.

methodsIn a cluster-randomized trial, sites were randomly assigned to the Greenlight intervention or an attention-control arm. Across 4 pediatric residency clinics, we enrolled infant-caregiver dyads at the 2-month well-child visit. Inclusion criteria included parent English- or Spanish-speaking and birth weight ≥1500 g. Designed with health-literacy principles, the intervention included a parent toolkit at each well-child visit, augmented by provider training in clear-health communication. The primary outcome was proportion of children overweight (BMI ≥85th percentile) at age 24 months. Secondary outcomes included weight status (BMI

resultsA total of 459 intervention and 406 control dyads were enrolled. In total, 49% of all children were overweight at 24 months. Adjusted odds for overweight at 24 months (treatment versus control) was 1.02 (95% confidence interval [CI]: 0.63 to 1.64). Adjusted mean BMI

conclusionsThe intervention resulted in less weight gain through age 18 months, which was not sustained through 24 months. Clinic-based interventions may be beneficial for early weight gain, but greater intervention intensity may be needed to maintain positive effects.

Indexed as

Health LiteracyChild, PreschoolCluster AnalysisEarly Medical InterventionFemaleHumansInfantMaleParentsPediatric ObesityPrevalenceWeight Gainand ChildrenCIconfidence intervalInfantsNew York UniversityNYUSupplemental Nutrition Program for WomenUMUNCUniversity of MiamiUniversity of North Carolina at Chapel HillVanderbilt University Medical CenterVUMCWCVwell-child visitWHOWICWorld Health Organization

Identifiers

PMID33911032
PMCPMC8086006
OpenAlexW3159564645

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.