Evidence map›Paper›PMID 33910879›Full record

Trial reportIn vivo (Athens, Greece)

Immune-modulating Effect of Korean Red Ginseng by Balancing the Ratio of Peripheral T Lymphocytes in Bile Duct or Pancreatic Cancer Patients With Adjuvant Chemotherapy.

Im-Kyung Kim, Kang Young Lee, Jeonghyun Kang, Joon Seong Park, Joon Jeong

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Evaluating the Hepatoprotective Effect ofFood science & nutrition · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Im-Kyung KimDepartment of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kang Young LeeDepartment of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Jeonghyun KangDepartment of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
Joon Seong ParkDepartment of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea jspark330@yuhs.ac jsjjoon@yuhs.ac.
Joon JeongDepartment of Surgery, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea jspark330@yuhs.ac jsjjoon@yuhs.ac.
Gangnam Severance Hospital · KRSeverance Hospital · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimWe aimed to clarify the clinical effect of Korean Red ginseng administered with adjuvant chemotherapy on the immune function of patients with bile duct or pancreatic cancer. PATIENTS AND

methodsThis was a prospective, randomized controlled trial conducted at a single tertiary center. Twenty-six consecutive patients who underwent curative resection for bile duct or pancreatic cancer followed by 5-fluorouracil/leucovorin or gemcitabine chemotherapy were included. They were randomized 1:1 to the ginseng and control groups. Immune and inflammatory markers were assayed in peripheral blood samples during and after chemotherapy.

resultsIntergroup differences in immune-related parameters before and during chemotherapy were not significant. After chemotherapy, the percentage of CD4

conclusionThe ginseng group, which received Korean Red ginseng daily during adjuvant chemotherapy, showed higher levels of CD4

Indexed as

PanaxPancreatic NeoplasmsBile DuctsChemotherapy, AdjuvantHumansProspective StudiesBile duct cancerchemotherapyimmune functionKorean Red ginsengpancreatic cancer

Identifiers

PMID33910879
PMCPMC8193343
OpenAlexW3159465565

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.