Evidence map›Paper›PMID 33910817›Full record

ReviewIn vivo (Athens, Greece)

Physiology and Pathology of Contractility of the Myometrium.

Antonios Koutras, Zacharias Fasoulakis, Athanasios Syllaios, Nikolaos Garmpis, Michail Diakosavvas, Athanasios Pagkalos, Thomas Ntounis, Emmanuel N Kontomanolis

Open access · diamondAbstract readReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A historical narrative review through the field of tocolysis in threatened preterm birth.European journal of obstetrics & gynecology and reproductive biology: X · 2024
    Review
  5. Article
  6. Article
  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Antonios KoutrasDepartment of Obstetrics and Gynecology, National and Kapodistrian University of Athens, General Hospital of Athens 'ALEXANDRA', Athens, Greece.
Zacharias FasoulakisDepartment of Obstetrics and Gynecology, National and Kapodistrian University of Athens, General Hospital of Athens 'ALEXANDRA', Athens, Greece.
Athanasios SyllaiosDepartment of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece; nh_reas@hotmail.com.
Nikolaos GarmpisDepartment of Surgery, National and Kapodistrian University of Athens, Laikon General Hospital, Athens, Greece.
Michail DiakosavvasDepartment of Obstetrics and Gynecology, National and Kapodistrian University of Athens, General Hospital of Athens 'ALEXANDRA', Athens, Greece.
Athanasios PagkalosConsultant on Department of Obstetrics and Gynecology, General Hospital of Xanthi, Xanthi, Greece.
Thomas NtounisDepartment of Obstetrics and Gynecology, National and Kapodistrian University of Athens, General Hospital of Athens 'ALEXANDRA', Athens, Greece.
Emmanuel N KontomanolisDepartment of Obstetrics and Gynecology, Democritus University of Thrace, Alexandroupolis, Greece.
National and Kapodistrian University of Athens · GRAlexandra Hospital · GRDemocritus University of Thrace · GRGeneral Hospital of Attica · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Uterine atony is a serious obstetrical complication since it is the leading cause of postpartum hemorrhage. Postpartum hemorrhage (PPH) is one of the 5 major causes of postpartum mortality; therefore, it requires immediate medical intervention, independent of whether delivery occurs normally or with a cesarean section. While in the past years most cases of postpartum hemorrhage were caused due to uterine atony following vaginal delivery, in recent years most PPH cases indicate a significant association with cesarean delivery. There are several methods used in order to avoid such a life-threatening complication, ranging from risk assessment to prevention, and finally medical intervention and management, if such an event occurs. In this scientific paper emphasis is given on the so-called "uterotonic" agents that are currently used, including oxytocin among others. It is, therefore, important to be familiar with these agents as well as understand the physiological mechanism by which they work, since they are used in everyday practice, not only for managing but also for preventing PPH. There are several potential questions that arise from the use of such "uterotonic" agents, and most specifically of oxytocin. Maybe one of the most important issues is the determination of optimal dosing of oxytocin in order to avoid PPH after a cesarean section.

Indexed as

OxytocicsPostpartum HemorrhageCesarean SectionFemaleHumansMyometriumOxytocinPregnancyOxytocicsOxytocincontractilitygestationMyometriumpostpartum hemorrhagereviewuterine atony

Identifiers

PMID33910817
PMCPMC8193291
OpenAlexW3157564037

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.