Evidence map›Paper›PMID 33910814›Full record

ReviewIn vivo (Athens, Greece)

Radiotherapy and Renal Cell Carcinoma: A Continuing Saga.

Despoina Spyropoulou, Panagiotis Tsiganos, Foteinos-Ioannis Dimitrakopoulos, Maria Tolia, Angelos Koutras, Dimitris Velissaris, Maria Lagadinou, Nikolaos Papathanasiou, Areti Gkantaifi, Haralabos Kalofonos and 1 more

Open access · diamondAbstract readReview
In one paragraph

Review in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Computed tomography-guided percutaneous biopsy in diagnosis of suspected metastatic renal cell carcinoma: which location is the most suitable?Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Despoina SpyropoulouDepartment of Radiation Oncology, University of Patras Medical School, Patras, Greece; spyrdespina@upatras.gr.
Panagiotis TsiganosClinical Radiology Laboratory, Department of Medicine, University of Patras, Patras, Greece.
Foteinos-Ioannis DimitrakopoulosDivision of Oncology, Department of Medicine, University Hospital of Patras, Patras, Greece.
Maria ToliaRadiotherapy Department, University Hospital Heraklion, University of Crete Medical School, Heraklion, Greece.
Angelos KoutrasDivision of Oncology, Department of Medicine, University Hospital of Patras, Patras, Greece.
Dimitris VelissarisEmergency Department and Internal Medicine Department, University Hospital of Patras, Patras, Greece.
Maria LagadinouEmergency Department University Hospital of Patras, Patras, Greece.
Nikolaos PapathanasiouNuclear Medicine and PET/CT Department, University Hospital of Patras, Patras, Greece.
Areti GkantaifiRadiotherapy Department, Interbalkan Medical Center, Thessaloniki, Greece.
Haralabos KalofonosDivision of Oncology, Department of Medicine, University Hospital of Patras, Patras, Greece.
Dimitrios KardamakisDepartment of Radiation Oncology, University of Patras Medical School, Patras, Greece.
General University Hospital of Patras · GRUniversity of Patras · GRInterbalkan Medical Center · GRUniversity of Crete · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Renal cell carcinoma (RCC) is one of the most aggressive malignancies of the genito-urinary tract, having a poor prognosis especially in patients with metastasis. Surgical resection remains the gold standard for localized renal cancer disease, with radiotherapy (RT) receiving much skepticism during the last decades. However, many studies have evaluated the role of RT, and although renal cancer is traditionally considered radio-resistant, technological advances in the RT field with regards to modern linear accelerators, as well as advanced RT techniques have resulted in breakthrough therapeutic outcomes. Additionally, the combination of RT with immune checkpoint inhibitors and targeted agents may maximize the clinical benefit. This review article focuses on the role of RT in the therapeutic management of renal cell carcinoma.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsHumansoligometastatic diseaseradioresistanceradiosensitivityradiotherapyRenal cell cancerreviewstereotactic body radiation therapy

Identifiers

PMID33910814
PMCPMC8193295
OpenAlexW3159399101

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.