Evidence map›Paper›PMID 33910645›Full record

ArticleEye and vision (London, England)2021

Modified endoscopic transnasal orbital apex decompression in dysthyroid optic neuropathy.

Yunhai Tu, Mingna Xu, Andy D Kim, Michael T M Wang, Zhaoqi Pan, Wencan Wu

Open access · diamondAbstract read
In one paragraph

Article in Eye and vision (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Association Between Peripheral IL-2Journal of clinical medicine · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Dysthyroid optic neuropathy: emerging treatment strategies.Journal of endocrinological investigation · 2023
    Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Yunhai Tu *The Eye Hospital of Wenzhou Medical University, No. 270 Xueyuan Xi Road, Wenzhou, Zhejiang, 325027, P. R. China.
Mingna Xu *The Eye Hospital of Wenzhou Medical University, No. 270 Xueyuan Xi Road, Wenzhou, Zhejiang, 325027, P. R. China.
Andy D KimDepartment of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand.
Michael T M WangDepartment of Ophthalmology, New Zealand National Eye Centre, The University of Auckland, Auckland, New Zealand.
Zhaoqi PanThe Eye Hospital of Wenzhou Medical University, No. 270 Xueyuan Xi Road, Wenzhou, Zhejiang, 325027, P. R. China.
Wencan WuThe Eye Hospital of Wenzhou Medical University, No. 270 Xueyuan Xi Road, Wenzhou, Zhejiang, 325027, P. R. China. wuwencan118@163.com.
Affiliated Eye Hospital of Wenzhou Medical College · CNUniversity of Auckland · NZWenzhou Medical University · CN

Funding

Natural Key Research and Development Program of China 2016YFC1101200
6 · The paper itself

Abstract

backgroundTo describe the surgical technique and assess the clinical efficacy and safety of modified endoscopic transnasal orbital apex decompression in the treatment of dysthyroid optic neuropathy.

methodsIn this retrospective research, forty-two subjects (74 orbits) who underwent modified endoscopic transnasal orbital apex decompression for the treatment of dysthyroid optic neuropathy were enrolled. Preoperative and postoperative best-corrected visual acuity (BCVA), visual field mean deviation (MD), Hertel exophthalmometry, and new onset diplopia were assessed before and after the intervention. The Wilcoxon test was used for differential analysis. Linear mixed-models' analyses were conducted to assess the potential predictors for BCVA change.

resultsPostoperatively, the mean BCVA improved from 0.70 ± 0.62 logMAR to 0.22 ± 0.33 logMAR. BCVA significantly improved in 69 eyes (93%), remained stable in 4 eyes (5%) and deteriorated in 1 eye (1%). MD of visual fields improved from -13.73 ± 9.22 dB to -7.23 ± 7.04 dB. Proptosis decreased from 19.57 ± 3.38 mm to 16.35 ± 3.01 mm. Preoperative BCVA, MD of visual fields and medical rectus diameter were independent factors associated with improvements in BCVA (P < 0.05) by linear mixed-models' analyses. Eighteen patients (42.9%) developed new diplopia postoperatively.

conclusionModified endoscopic transnasal orbital apex decompression effectively restores vision in dysthyroid optic neuropathy.

Indexed as

Dysthyroid optic neuropathyEndoscopic transnasal orbital decompressionThyroid-associated ophthalmopathyVisual acuityVisual field

Identifiers

PMID33910645
PMCPMC8080388
OpenAlexW3159761785

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.