Evidence map›Paper›PMID 33910579›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2021

Non-contrast cardiovascular magnetic resonance detection of myocardial fibrosis in Duchenne muscular dystrophy.

Frank J Raucci, Meng Xu, Kristen George-Durrett, Kimberly Crum, James C Slaughter, David A Parra, Larry W Markham, Jonathan H Soslow

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Role of cardiovascular magnetic resonance in diagnosis and management of muscular dystrophies.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Article
  13. Localized strain characterization of cardiomyopathy in Duchenne muscular dystrophy using novel 4D kinematic analysis of cine cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023
    Article
  14. Article
  15. Myocardial strain imaging in Duchenne muscular dystrophy.Frontiers in cardiovascular medicine · 2022
    Review
  16. Article
  17. Global, segmental and layer specific analysis of myocardial involvement in Duchenne muscular dystrophy by cardiovascular magnetic resonance native T1 mapping.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Frank J RaucciThomas P Graham Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA. frank.raucci@vcuhealth.org.ORCID 0000-0002-3464-6569
Meng XuDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
Kristen George-DurrettThomas P Graham Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Kimberly CrumThomas P Graham Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
James C SlaughterDepartment of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA.
David A ParraThomas P Graham Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Larry W MarkhamDivision of Cardiology, Department of Pediatrics, Riley Hospital for Children at Indiana University Health, Indianapolis, IN, USA.
Jonathan H SoslowThomas P Graham Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.
Vanderbilt University Medical Center · USChildren's Hospital of Richmond at VCU · USIndiana University Health · US

Funding

Vanderbilt Institute for Clinical and Translational Research (VICTR) -Identifying correlates of functional immunity in SARS-CoV-2 convalescent plasmaUL1TR002243 · NCATS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Paul A. Harris, Wesley H Self · 2017 to 2026
$130.7M
Pathogenesis, Targeted Therapeutics, and New Vaccines for Childhood DiseaseK12HD087023 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Michael R. DeBaun, Juan C Salazar · 2016 to 2026
$4.1M
Prospective Development of a Multimodal Biomaker Platform for Predictive Risk Stratification of Cardiac Disease in Duchenne Muscular DystrophyR01FD006649 · FDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SOSLOW, JONATHAN HARVEY · 2019 to 2024
$2.5M
Quantitative Assessment of Cardiac Disease in Duchenne Muscular DystrophyK23HL123938 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SOSLOW, JONATHAN HARVEY · 2014 to 2018
$829k
Development of a Multimodal Biomaker Platform for Predictive Risk Stratification of Cardiac Disease in Duchenne Muscular DystrophyR56HL141248 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SOSLOW, JONATHAN HARVEY · 2018 to 2018
$769k
Targeting Pannexin 1 as a Novel Mechanism for Arrhythmia and Fibrosis in Duchenne CardiomyopathyK08HL155852 · NHLBI · VIRGINIA COMMONWEALTH UNIVERSITY · PI RAUCCI, FRANK J · 2021 to 2025
$742k
Role of Pannexin Channels in Arrhythmogenesis and Cardiac Fibrosis in Models of Duchenne Muscular DystrophyF32HL137394 · NHLBI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RAUCCI, FRANK J · 2017 to 2018
$118k
FDA HHS R01 FD006649NCATS NIH HHS UL1 TR002243NHLBI NIH HHS F32HL137394NHLBI NIH HHS K08 HL155852NHLBI NIH HHS K23 HL123938NHLBI NIH HHS R56HL141248NICHD NIH HHS K12 HD087023
6 · The paper itself

Abstract

backgroundDuchenne muscular dystrophy (DMD) leads to progressive cardiomyopathy. Detection of myocardial fibrosis with late gadolinium enhancement (LGE) by cardiovascular magnetic resonance (CMR) is critical for clinical management. Due to concerns of brain deposition of gadolinium, non-contrast methods for detecting and monitoring myocardial fibrosis would be beneficial.

objectivesWe hypothesized that native T1 mapping and/or circumferential (ε

methods156 CMRs with gadolinium were performed in 66 DMD boys and included: (1) left ventricular ejection fraction (LVEF), (2) LGE, (3) native T1 mapping and myocardial tagging (ε

resultsMean age and LVEF at first CMR were 14 years and 54%, respectively. Global ε

conclusionsPre-contrast sequences predict presence and severity of LGE, with ε

Indexed as

CardiomyopathiesMuscular Dystrophy, DuchenneContrast MediaFibrosisGadoliniumHumansMagnetic Resonance Imaging, CineMagnetic Resonance SpectroscopyMaleMyocardiumPredictive Value of TestsStroke VolumeVentricular Function, LeftContrast MediaGadoliniumCardiac fibrosisCircumferential strainDuchene muscular dystrophyLate gadolinium enhancementNative T1

Identifiers

PMID33910579
PMCPMC8082768
OpenAlexW3158153549

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.