Evidence map›Paper›PMID 33910571›Full record

ArticleJournal of nanobiotechnology2021

Phagocytosis of polymeric nanoparticles aided activation of macrophages to increase atherosclerotic plaques in ApoE

Tieying Yin, Yanhong Li, Yuzhen Ren, Atik Rohmana Maftuhatul Fuad, Fangfang Hu, Ruolin Du, Yang Wang, Guixue Wang, Yazhou Wang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Wrapping anisotropic microgel particles in lipid membranes: Effects of particle shape and membrane rigidity.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  14. Review
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 2 countries.

Tieying YinKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China. tieying_yin@cqu.edu.cn.ORCID http://orcid.org/0000-0002-0424-776X
Yanhong LiKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Yuzhen RenKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Atik Rohmana Maftuhatul FuadKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Fangfang HuKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Ruolin DuKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Yang WangKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Guixue WangKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China.
Yazhou WangKey Laboratory for Biorheological Science and Technology of Ministry of Education, State and Local Joint Engineering Laboratory for Vascular Implants, Bioengineering College of Chongqing University, Chongqing, 400044, China. yazhou_wang@cqu.edu.cn.
Chongqing University · CN

Funding

the Fundamental Research Funds for the Central Universities 2019CDYGZD002the Fundamental Research Funds for the Central Universities 2020CDCGJ011the National Natural Science Foundation of China 12032007the National Natural Science Foundation of China 31971242the Natural Science Foundation of Chongqing cstc2019jcyj-19zdxmX0009the Natural Science Foundation of Chongqing cstc2019jcyj-msxmX0307the Natural Science Foundation of Chongqing cstc2019jcyj-zdxmX0028
6 · The paper itself

Abstract

The unique physiochemical properties of nanomaterials have been widely used in drug delivery systems and diagnostic contrast agents. The safety issues of biomaterials with exceptional biocompatibility and hemo-compatibility have also received extensive attention at the nanoscale, especially in cardiovascular disease. Therefore, we conducted a study of the effects of poly (lactic-co-glycolic acid) nanoparticles (PLGA NPs) on the development of aortic atherosclerotic plaques in ApoE

Indexed as

AnimalsApolipoproteins EAtherosclerosisBiocompatible MaterialsDrug CarriersDrug Delivery SystemsFoam CellsInterleukin-6Lipoproteins, LDLMacrophagesMaleMiceMice, Inbred C57BLNanoparticlesParticle SizePhagocytosisApolipoproteins EBiocompatible MaterialsDrug CarriersInterleukin-6Lipoproteins, LDLoxidized low density lipoproteinPolyglycolic AcidPolylactic Acid-Polyglycolic Acid CopolymerTumor Necrosis Factor-alphaAtherosclerosisFoam cellMacrophagesNanomedicinePhagocytosis

Identifiers

PMID33910571
PMCPMC8082811
OpenAlexW3111753241

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.